Theses
Lower-level publication types
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Bachelor Thesis [160]
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Doctoral Thesis [29838]
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Habilitation Thesis [192]
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Master Thesis [2015]
Recent Submissions
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BUI LDINGS B LOCKS TOWARDS FUL LY INT EGRAT ED HIGH- FREQUENCY POWER E L ECTRONIC DEVICE S
(2024)Limiting climate change is closely linked to the energy transition from fossil fuels to sustainable energy sources and the intelligent electrification of energy supply and consumption. This process is accompanied by the implementation of wide bandgap semiconductors such as SiC and the adjustment of the whole device packaging including all components and material systems. In this spirit, this work focuses on some crucial building blocks ...Doctoral Thesis -
THE BIOGEOGRAPHY OF KEY FUNCTIONAL TRAITS AND COMMUNITY STRUCTURES ACROSS GLOBAL FORESTS
(2024)Doctoral Thesis -
Taming Reactive Nitrogen Intermediates for Amination and Deaminative Coupling Reactions
(2024)Doctoral Thesis -
Taming Reactive Nitrogen Intermediates for Amination and Deaminative Coupling Reactions
(2024)Doctoral Thesis -
Taming Reactive Nitrogen Intermediates for Amination and Deaminative Coupling Reactions
(2023)Doctoral Thesis -
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Non-Convex Optimization in Networks and High-Dimensional Covariance Estimation
(2024)In this thesis, we consider two sub-fields of Mathematics, on the one hand Mathematics of Data Science, on the other hand High-Dimensional Probability. The first part of this work is dedicated to problems in non-convex optimization arising in inverse problems on networks and synchronization in complex networks. The second part is dedicated to robust estimation of covariance matrices of high-dimensional vectors, mainly in the context of ...Doctoral Thesis -
Die direkte fahrzeugseitige Messung der akustischen Schienenrauheit
(2024)Auf dem Weg zur umweltfreundlichen Mobilität wächst die Bedeutung des Schienenverkehrs. In Zukunft wird in der Schweiz ein weiterer Anstieg des Fahrgast- und Güteraufkommens im Schienenverkehr erwartet. Die steigende Nachfrage ist mit einer höheren Anzahl an Fahrten verbunden und es ist mit einer stärkeren Belastung der Schieneninfrastruktur zu rechnen. Dies stellt sowohl die Instandhaltung als auch den Lärmschutz vor neue Herausforderungen. ...Doctoral Thesis -
Physics-informed Probabilistic Artificial Intelligence for Enhanced Stability Predictions in Milling
(2024)With the widespread use of milling operations in the manufacturing industry, there has been a consistent desire to operate machine tools at their highest material removal rate capacity. Such an increase in productivity brings economic and environmental benefits by reducing the production time per item, subsequently leading to reductions in production costs, energy consumption, and related expenses. Despite this enduring aspiration, the ...Doctoral Thesis -
Carbon Isotopes and a Laser: Towards Simultaneous Measurements
(2024)The technique of laser ablation accelerator mass spectroscopy (LA-AMS) has been developed and improved over the past decade. It promises faster and cheaper high-resolution ¹⁴C records of various carbonate archives, but these benefits come at the cost of measurement precision. Here, a routine analysis protocol is proposed, which can reduce uncertainties by about 55%. It achieves this by measuring two parallel tracks, applying a Savitzky-Golay ...Doctoral Thesis -
Application of CLIR-MS in cell extract to map RNA-protein interactions in the context of SMN and FECH alternative splicing
(2024)The genetic information present in the DNA is transcribed into RNA, which must undergo a series of maturation steps before it can be translated into functional proteins. Splicing is a major step in pre-mRNA maturation, during which introns are removed and exons are ligated to form mature mRNAs. In higher eukaryotes, splice sites are often degenerate and additional factors are then required to allow the correct recognition of the 5’ and ...Doctoral Thesis -
Characterization of complexes required for mammalian transcriptional and post transcriptional gene regulation
(2024)Integrator (INT) is a large protein complex in metazoans, containing at least 16 subunits with a combined molecular weight of more than 1.5 MDa. This modular complex harbors dual enzymatic functionality with a cleavage module that has RNA endonuclease activity, and a phosphatase module with phosphatase activity. INT was initially identified as the 3’-end processing machinery for uridine-rich small nuclear RNAs (UsnRNAs). Later, it was ...Doctoral Thesis -
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Exploiting genetic variation in barley to elucidate factors determining starch granule morphology in the cereal endosperm
(2024)Plants polymerize simple sugars into starch that is stored as water-insoluble, semi-crystalline starch granules. It is present in the form of transitory starch located in the chloroplasts of leaves as a product of photosynthesis and as storage starch accumulated in the amyloplasts of seeds and tubers, including our staple crop plants. While transitory starch granules show similar morphologies across organisms, storage starch granules ...Doctoral Thesis -
Monitoring, Modelling and Control for Increasing Repeatability of Thermal Spraying
(2024)There is a need to increase the repeatability of coating characteristics produced by thermal spraying processes – to meet tighter coating tolerances, improve process yield, reduce waste and the need for part reworking, saving time and costs. Increasing the repeatability is challenging because the characteristics of the produced coatings are influenced by multiple tens of parameters and their complex interactions. Solving this problem ...Doctoral Thesis -
Post-transcriptional regulation orchestrated by Regnase RNA-binding proteins and m6A RNA methylation controls mast cell activation and homeostasis
(2024)Mast cells (MCs) are long-lived, tissue-resident immune cells with a central role in allergic responses. These cells can be activated by a wide range of stimuli leading to secretion of a large array of inflammatory mediators. Dysregulation of this process leads to allergies, asthma and anaphylaxis. Tight control is therefore critical to facilitate effective immune responses against external threats while minimizing harm to the host. ...Doctoral Thesis -
Microplastic in soil - waterdynamics, hydrophobicity, and interactions
(2024)Soils are considered as large sinks of microplastic (MP, diameter < 5 mm). Sources of MP contamination are identified as mismanagement of plastic containing waste, the use of plastics in agriculture as well as the neglected life cycle of plastic containing products. The long-range transport of airborne MP, its subsequent deposition and the degradation of larger plastic fragments are a potential source and pathway of MP input into soils. ...Doctoral Thesis -
Evaluating interventions and defence mechanisms in bacterial symbiosis and pathobionts
(2024)Doctoral Thesis -
Mechanisms that link climate, soil properties and microbes to macroscale soil organic carbon dynamics: Insights from a geoclimatic gradient
(2024)Adequate representation of the soil organic carbon (SOC) cycle at the macroscale (km to global) is important in order to understand and predict the implications of SOC dynamics for the climate and our planet. Such adequate representation is challenging, because mechanistic knowledge about soils is derived from the much smaller mesoscale (mm to m). However, the dominant mechanisms and controls of the SOC cycle vary across scales. Therefore, ...Doctoral Thesis -