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Recently Added
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Spatially mapping thermal transport in graphene by an optothermal method
(2022)NPJ 2D MATERIALS AND APPLICATIONSMapping the thermal transport properties of materials at the nanoscale is of critical importance for optimizing heat conduction in nanoscale devices. Several methods to determine the thermal conductivity of materials have been developed, most of them yielding an average value across the sample, thereby disregarding the role of local variations. Here, we present a method for the spatially resolved assessment of the thermal conductivity of ...Journal Article -
Fragile X-Related Protein 1 Regulates Nucleoporin Localization in a Cell Cycle-Dependent Manner
(2021)Frontiers in Cell and Developmental BiologyNuclear pore complexes (NPCs) are embedded in the nuclear envelope (NE) where they ensure the transport of macromolecules between the nucleus and the cytoplasm. NPCs are built from nucleoporins (Nups) through a sequential assembly order taking place at two different stages during the cell cycle of mammalian cells: at the end of mitosis and during interphase. In addition, fragile X-related proteins (FXRPs) can interact with several cytoplasmic ...Journal Article -
Benchmarking Molecular Feature Attribution Methods with Activity Cliffs
(2022)JOURNAL OF CHEMICAL INFORMATION AND MODELINGFeature attribution techniques are popula r choices within the explainable artificial intelligence toolbox, as they can help elucidate which parts of the provided inputs used by an underlying supervised-learning method are considered relevant for a specific prediction. In the context of molecular design, these approaches typically involve the coloring of molecular graphs, whose presentation to medicinal chemists can be useful for making ...Journal Article -
Unveiling wide-orbit companions to K-type stars in Sco-Cen with Gaia EDR3
(2022)Astronomy & AstrophysicsContext. The detection of low-mass companions to stellar hosts is important for testing the formation scenarios of these systems. Companions at wide separations are particularly intriguing objects as they are easily accessible for variability studies of the rotational dynamics and cloud coverage of these brown dwarfs or planetary-mass objects. Aims. We aim to identify new low-mass companions to young stars using the astrometric measurements ...Journal Article -
Evidence for Effects of Extracellular Vesicles on Physical, Inflammatory, Transcriptome and Reward Behaviour Status in Mice
(2022)International Journal of Molecular SciencesImmune-inflammatory activation impacts extracellular vesicles (EVs), including their miRNA cargo. There is evidence for changes in the EV miRNome in inflammation-associated neuropsychiatric disorders. This mouse study investigated: (1) effects of systemic lipopolysaccharide (LPS) and chronic social stress (CSS) on plasma EV miRNome; and (2) physiological, transcriptional, and behavioural effects of peripheral or central delivered LPS-activated ...Journal Article