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Recently Added 

  1. Chemically Synthesized, Self-Assembling Small Interfering RNA-Prohead RNA Molecules Trigger Dicer-Independent Gene Silencing 

    Hill, Alyssa C.; van Leeuwen, Daniel; Schlosser, Verena; et al. (2022)
    Chemistry - A European Journal
    RNA interference (RNAi) mediated by small interfering RNA (siRNA) duplexes is a powerful therapeutic modality, but the translation of siRNAs from the bench into clinical application has been hampered by inefficient delivery in vivo. An innovative delivery strategy involves fusing siRNAs to a three-way junction (3WJ) motif derived from the phi29 bacteriophage prohead RNA (pRNA). Chimeric siRNA-3WJ molecules are presumed to enter the RNAi ...
    Journal Article
  2. Ten years of Catalysis Science & Technology 

    Perez-Ramirez, Javier (2022)
    Catalysis Science & Technology
    Other Journal Item
  3. Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study 

    Jablonski, Kim Philipp; Carron, Leopold; Mozziconacci, Julien; et al. (2022)
    HUMAN GENOMICS
    Background Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the mechanisms underlying the association. Based on the recent discovery that changes in three-dimensional genome organization may have functional consequences on gene regulation favoring diseases, we ...
    Journal Article
  4. Thermodynamically admissible 13-moment equations 

    Struchtrup, Henning; Ottinger, Hans Christian (2022)
    Physics of Fluids
    Grad's 13-moment equations describe transport in mildly rarefied gases well, but are not properly embedded into nonequilibrium thermodynamics since they are not accompanied by a formulation of the second law. In this work, the Grad-13 equations are embedded into the framework of GENERIC (general equation for the nonequilibrium reversible-irreversible coupling), which demands additional contributions in the equations to guarantee thermodynamic ...
    Journal Article

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