Journal: Obesity Surgery

Abbreviation

Obes Surg

Publisher

Springer

Journal Volumes

ISSN

0960-8923
1708-0428

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2013 - 201992020 - 20231
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Publications 1 - 10 of 10
  • Waist Circumference and Related Anthropometric Indices Are Associated with Metabolic Traits in Severely Obese Subjects
    Item type: Journal Article
    Zazai, Runa; Wilms, Britta; Ernst, Barbara; et al. (2014)
    Obesity Surgery
    Increased waist circumference (WC) and related anthropometric indices have been shown to be, independently of body weight and body mass index (BMI), associated with adverse metabolic traits in many populations. It is unknown, however, whether WC also predicts adverse metabolic traits in severely obese subjects displaying a BMI greater than 35 kg/m2. To address this question, we analyzed a dataset including 838 severely obese patients (597 women, BMI 44.6 ± 6.2 kg/m2; 241 men, BMI 44.3 ± 5.7 kg/m2). Body weight, height, WC, hip circumference, and blood pressure were measured in all subjects along with the following metabolic blood markers: fasting glucose, insulin, glycolized hemoglobin levels, triglycerides, total cholesterol, low- and high-density cholesterol, and uric acid. Multivariate regression analyses indicated that WC as well as related anthropometric indices, in particular those accounting for subjects’ height, were associated with many metabolic variables independently of body weight and BMI. In general, height-adjusted WC indices were more closely associated with metabolic traits in women than in men. Collectively, our findings suggest that body fat distribution also plays an important role in determining metabolic traits in severely obese subjects and that WC represents a valuable marker of abdominal/visceral obesity in this population.
  • Severe Abdominal Pain After Bariatric Surgery: Think Twice-Think Porphyria!
    Item type: Other Journal Item
    Vielhaber, Jochen A.; Barman-Aksözen, Jasmin; Minder, Elisabeth I.; et al. (2023)
    Obesity Surgery
  • Letter to the Editor: Circulating Adult Stem and Progenitor Cells After Roux-en-Y Gastric Bypass Surgery in Myotonic Dystrophy
    Item type: Other Journal Item
    Kröpfl, Julia M.; Wilms, Britta; Ernst, Barbara; et al. (2019)
    Obesity Surgery
  • Quantification of Liver, Subcutaneous, and Visceral Adipose Tissues by MRI Before and After Bariatric Surgery
    Item type: Journal Article
    Meyer-Gerspach, Anne Christin; Peterli, Ralph; Moor, Michael; et al. (2019)
    Obesity Surgery
    Background: Morbid obesity is a worldwide epidemic and is increasingly treated by bariatric surgery. Fatty liver is a common finding; almost half of all patients with non-alcoholic steatohepatitis develop steatohepatitis. Bariatric surgery improves steatohepatitis documented by liver biopsy and single voxel magnetic resonance imaging (MRI) techniques. Objective: To investigate changes before and after bariatric surgery using whole organ MRI quantification of liver, visceral, and subcutaneous fat. Setting: University of Basel Hospital and St. Clara Research Ltd, Basel, Switzerland. Methods: Sixteen morbidly obese patients were evaluated by abdominal MRI-scanning before and 3, 6, 12, and 24 months after bariatric surgery to measure percentage liver fat (%-LF), total liver volume (TLV) and visceral and subcutaneous adipose tissues (VAT and SAT). Fasting plasma samples were taken for measurement of glucose, insulin, blood lipids, and liver biomarkers. In a control group of 12 healthy lean volunteers, the liver biomarker was also measured. Results: The reproducibility of fat quantification by use of MRI was excellent. LF decreased significantly faster than VAT and SAT (%-LF vs. VAT p < 0.001 and %-LF vs. SAT p < 0.001). At certain time points, %-LF, VAT, and SAT were associated with changes in blood lipids and insulin. Conclusions: MRI quantification offers excellently reproducible results in measurement of liver fat and visceral and subcutaneous adipose tissues. Liver fat decreased significantly faster than visceral or subcutaneous adipose tissue. Decrease in %-LF and VAT is associated with decrease in total cholesterol, LDL, and plasma insulin.
  • Roux-en-Y gastric Bypass surgery rapidly improves beta cell`s Insulin processing in severely obese type 2 diabetic patients
    Item type: Other Conference Item
    Svehlikova, Eva; Pieber, Thomas R.; Tuca, Alexandrou; et al. (2014)
    Obesity Surgery
  • Roux-en Y Gastric Bypass Surgery Reduces Hedonic Hunger and Improves Dietary Habits in Severely Obese Subjects
    Item type: Journal Article
    Ullrich, Jennifer; Ernst, Barbara; Wilms, Britta; et al. (2013)
    Obesity Surgery
  • Reduced Circulating Androgen Levels After Gastric Bypass Surgery in Severely Obese Women
    Item type: Journal Article
    Ernst, Barbara; Wilms, Britta; Thurnheer, Martin; et al. (2013)
    Obesity Surgery
  • Differential Changes in Physical Performance Three Month after Bariatric Surgery
    Item type: Other Conference Item
    Schultes, B.; Waldburger, R.; Zazai, R.; et al. (2014)
    Obesity Surgery
  • Preoperative Nutritional Deficiencies in Severely Obese Bariatric Candidates are not Linked to Gastric Helicobacter pylori Infection
    Item type: Journal Article
    Gerig, Rahel; Ernst, Barbara; Wilms, Britta; et al. (2013)
    Obesity Surgery
    Severely obese subjects have been found to show a high prevalence of distinct nutritional deficiencies even without any bariatric intervention but the underlying reasons remain obscure. We tested the hypothesis that gastric Helicobacter pylori infection is associated with increased nutritional deficiency rates. Taking advantage of our large database, we identified 404 patients who had undergone a gastroscopy - as a standard diagnostic assessment before bariatric surgery - along with a histological examination of gastric mucosal biopsies with concurrent nutritional blood measurements. Eighty-five (21 %) of the obese patients included in the study displayed a gastric H. pylori infection. Sex distribution, age and body mass index did not differ between H. pylori+ and H. pylori- patients (P > 0.29). Referring to nutritional markers, neither serum levels of total protein, albumin, calcium, phosphate, magnesium, ferritin, zinc, copper, vitamin B12, folate and 25-OH vitamin D 3 nor respective deficiency rates differed between the H. pylori+ and H. pylori- patients group (all P > 0.13). Overall, 49.5 % of the bariatric candidates displayed at least one nutritional deficiency. Our data confirm previous reports on high prevalences of nutritional deficiencies in severely obese subjects. However, they do not provide evidence for a contributing role of gastric H. pylori infection to these nutritional alterations. © 2013 Springer Science+Business Media New York.
Publications 1 - 10 of 10