The Journal of Immunology

Journal: The Journal of Immunology

Abbreviation

J Immunol

Publisher

AAI

ISSN

0022-1767
1048-3233
1047-7381
1550-6606

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Publications 1 - 10 of 51

The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 Type III Secretion Systems Allow Salmonella Serovar typhimurium to Trigger Colitis via MyD88-Dependent and MyD88-Independent Mechanisms
Hapfelmeier, Siegfried; Stecher, Bärbel; Barthel, Manja; et al. (2005)
The Journal of Immunology
A Novel Th Cell Epitope of Candida albicans Mediates Protection from Fungal Infection
Bär, Eva; Gladiator, André; Bastidas, Sonia; et al. (2012)
The Journal of Immunology
Caspase-4 Is Required for Activation of Inflammasomes
Sollberger, Gabriel; Strittmatter, Gerhard E.; Kistowska, Magdalena; et al. (2012)
The Journal of Immunology
MyD88-Dependent IFN-γ Production by NK Cells Is Key for Control of Legionella pneumophila Infection
Spörri, Roman; Joller, Nicole; Albers, Urs; et al. (2006)
The Journal of Immunology
The MHC Class II Immunopeptidome of Lymph Nodes in Health and in Chemically Induced Colitis
Fugmann, Tim; Sofron, Adriana; Ritz, Danilo; et al. (2016)
The Journal of Immunology
Response to Comment on “Nonhematopoietic Cells Are Key Players in Innate Control of Bacterial Airway Infection”
LeibundGut-Landmann, Salomé; Oxenius, Annette (2011)
The Journal of Immunology
CXCR3 Identifies Human Naive CD8⁺ T Cells with Enhanced Effector Differentiation Potential
De Simone, Gabriele; Mazza, Emilia M.C.; Cassotta, Antonino; et al. (2019)
The Journal of Immunology
n mice, the ability of naive T (TN) cells to mount an effector response correlates with TCR sensitivity for self-derived Ags, which can be quantified indirectly by measuring surface expression levels of CD5. Equivalent findings have not been reported previously in humans. We identified two discrete subsets of human CD8+ TN cells, defined by the absence or presence of the chemokine receptor CXCR3. The more abundant CXCR3+ TN cell subset displayed an effector-like transcriptional profile and expressed TCRs with physicochemical characteristics indicative of enhanced interactions with peptide–HLA class I Ags. Moreover, CXCR3+ TN cells frequently produced IL-2 and TNF in response to nonspecific activation directly ex vivo and differentiated readily into Ag-specific effector cells in vitro. Comparative analyses further revealed that human CXCR3+ TN cells were transcriptionally equivalent to murine CXCR3+ TN cells, which expressed high levels of CD5. These findings provide support for the notion that effector differentiation is shaped by heterogeneity in the preimmune repertoire of human CD8+ T cells.
Mechanisms of neonatal mucosal antibody protection
Harris, Nicola L.; Spoerri, Iris; Schopfer, Jacqueline F.; et al. (2006)
The Journal of Immunology
Learning the high-dimensional immunogenomic features that predict public and private antibody repertoires
Greiff, Victor; Weber, Cédric R.; Palme, Johannes; et al. (2017)
The Journal of Immunology
Functional Properties and Lineage Relationship of CD8+ T Cell Subsets Identified by Expression of IL-7 Receptor α and CD62L
Bachmann, Martin F.; Wolint, Petra; Schwarz, Katrin; et al. (2005)
The Journal of Immunology

Publications 1 - 10 of 51

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