Journal: Spine
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Lippincott Williams & Wilkins
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Publications1 - 10 of 22
- The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus–mediated pain in vitro and in vivoItem type: Journal Article
SpineWuertz, Karin; Quero, Lilian; Sekiguchi, Miho; et al. (2011) - Neurophysiological Effects of High Velocity and Low Amplitude Spinal Manipulation in Symptomatic and Asymptomatic Humans: A Systematic Literature ReviewItem type: Journal Article
SpineWirth, Brigitte; Gassner, Antonia; de Bruin, Eling; et al. (2019) - Changes in bone architecture during spinal fusionItem type: Journal Article
SpineSmit, Theo H.; Müller, Ralph; Dijk, Martijn van; et al. (2003) - Is There an Association Between Pain and Magnetic Resonance Imaging Parameters in Patients With Lumbar Spinal Stenosis?Item type: Review Article
SpineBurgstaller, Jakob M.; Schüffler, Peter J.; Buhmann, Joachim M.; et al. (2016) - Biological response of the intervertebral disc to repetitive short-term cyclic torsionItem type: Journal Article
SpineChan, Samantha C.W.; Ferguson, Stephen J.; Wuertz, Karin; et al. (2011) - Quantitative magnetic resonance imaging of enzymatically induced degradation of the nucleus pulposus of intervertebral discsItem type: Journal Article
SpineAntoniou, J.; Mwale, F.; Demers, C. N.; et al. (2006) - The Biomechanics of the Transpedicular Endoscopic ApproachItem type: Journal Article
SpineMeisterhans, Michel; Hagel, Vincent; Spirig, José; et al. (2024)Study Design: Biomechanical cadaveric study. Objective: The goal of this study was to analyze the effects of an endoscopic transpedicular approach with different drill diameters (6 and 8 mm) and compare them with the intact native side. In addition, the influence of bone quality on the resistance of the pedicle was investigated. Summary of Background Data: Clinical studies have repeatedly highlighted the benefits of endoscopic transpedicular decompression for downmigrated lumbar disc herniations. However, the biomechanical effects on pedicle stability have not been studied up to now. Materials and Methods: Twenty-four vertebras originating from four fresh-frozen cadavers were tested under uniaxial compression load in a ramp-to-failure test: (1) the tunneled pedicle on one side, and (2) the native pedicle on the other side. Twelve lumbar vertebrae were assigned to drill diameter of 6 mm and the other 12 to diameter of 8 mm. Results: The median ratio of sustained force for the operated side compared with the intact contralateral side is equal to 74% (63–88) for both drill diameters combined. An 8 mm transpedicular approach recorded an axial resistance of 77% (60–88) compared with the intact contralateral side (P=0.002). A 6 mm approach resulted in an axial resistance of 72% (66–84) compared with the intact opposite side (P=0.01). No significant difference between the two different drill diameters was recorded (P=1). For all three subgroups (intact, 8 mm, 6 mm) the Hounsfield units-values and the absolute resistance force showed significant correlations (intact: ρ=0.859; P<0.001; 8 mm: ρ=0.902; P<0.001; 6 mm: ρ=0.835; P<0.001). Conclusion: The transpedicular approach significantly reduces the axial resistance force of the pedicle, which may lead to pedicle fracture. Bone quality correlated positively with the absolute resistance force of the pedicle, whereas the influence of the drill hole diameter plays only a limited role. - Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral discItem type: Journal Article
SpineWuertz, Karin; Godburn, Karolyn; Neidlinger-Wilke, Cornelia; et al. (2008) - Peroxynitrite induces gene expression in intervertebral disc cellsItem type: Journal Article
SpinePoveda, Lucy; Hottiger, Michael O.; Boos, Norbert; et al. (2009) - Implant Design and the Anchoring Mechanism Influence the Incidence of Heterotopic Ossification in Cervical Total Disc Replacement at 2-year Follow-upItem type: Journal Article
SpineMehren, Christoph; Würtz-Kozak, Karin; Sauer, Daniel; et al. (2019)
Publications1 - 10 of 22