Journal of Cardiovascular Magnetic Resonance

Journal: Journal of Cardiovascular Magnetic Resonance

Abbreviation

J Cardiovasc Magn Reson

Publisher

Taylor & Francis

ISSN

1097-6647
1532-429X

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Publications 1 - 8 of 8

Retrospective respiratory motion correction for navigated cine velocity mapping
Baltes, Christof; Kozerke, Sebastian; Atkinson, David; et al. (2004)
Journal of Cardiovascular Magnetic Resonance
2D-Spatially-Selective Real-Time Magnetic Resonance Imaging for the Assessment of Microvascular Function and Its Relation to the Cardiovascular Risk Profile
Schwitter, Juerg; Oelhafen, Markus; Wyss, Barbara M.; et al. (2006)
Journal of Cardiovascular Magnetic Resonance
Is Post-Systolic Shortening a Reliable Indicator of Myocardial Viability? An MR Tagging and Late-Enhancement Study
Ryf, Salome; Rutz, Andrea K.; Bösiger, Peter; et al. (2006)
Journal of Cardiovascular Magnetic Resonance
The relationship between myocardial microstructure and strain in chronic infarction using cardiovascular magnetic resonance diffusion tensor imaging and feature tracking
Sharrack, Noor; Das, Arka; Kelly, Christopher; et al. (2022)
Journal of Cardiovascular Magnetic Resonance
Background: Cardiac diffusion tensor imaging (cDTI) using cardiovascular magnetic resonance (CMR) is a novel technique for the non-invasive assessment of myocardial microstructure. Previous studies have shown myocardial infarction to result in loss of sheetlet angularity, derived by reduced secondary eigenvector (E2A) and reduction in subendocardial cardiomyocytes, evidenced by loss of myocytes with right-handed orientation (RHM) on helix angle (HA) maps. Myocardial strain assessed using feature tracking-CMR (FT-CMR) is a sensitive marker of sub-clinical myocardial dysfunction. We sought to explore the relationship between these two techniques (strain and cDTI) in patients at 3 months following ST-elevation MI (STEMI). Methods: 32 patients (F = 28, 60 ± 10 years) underwent 3T CMR three months after STEMI (mean interval 105 ± 17 days) with second order motion compensated (M2), free-breathing spin echo cDTI, cine gradient echo and late gadolinium enhancement (LGE) imaging. HA maps divided into left-handed HA (LHM, − 90 < HA < − 30), circumferential HA (CM, − 30° < HA < 30°), and right-handed HA (RHM, 30° < HA < 90°) were reported as relative proportions. Global and segmental analysis was undertaken. Results: Mean left ventricular ejection fraction (LVEF) was 44 ± 10% with a mean infarct size of 18 ± 12 g and a mean infarct segment LGE enhancement of 66 ± 21%. Mean global radial strain was 19 ± 6, mean global circumferential strain was − 13 ± − 3 and mean global longitudinal strain was − 10 ± − 3. Global and segmental radial strain correlated significantly with E2A in infarcted segments (p = 0.002, p = 0.011). Both global and segmental longitudinal strain correlated with RHM of infarcted segments on HA maps (p < 0.001, p = 0.003). Mean Diffusivity (MD) correlated significantly with the global infarct size (p < 0.008). When patients were categorised according to LVEF (reduced, mid-range and preserved), all cDTI parameters differed significantly between the three groups. Conclusion: Change in sheetlet orientation assessed using E2A from cDTI correlates with impaired radial strain. Segments with fewer subendocardial cardiomyocytes, evidenced by a lower proportion of myocytes with right-handed orientation on HA maps, show impaired longitudinal strain. Infarct segment enhancement correlates significantly with E2A and RHM. Our data has demonstrated a link between myocardial microstructure and contractility following myocardial infarction, suggesting a potential role for CMR cDTI to clinically relevant functional impact.
Accelerated tagging for the assessment of left ventricular myocardial contraction under physical stress
Ryf, Salome; Schwitter, Jürg; Spiegel, Marcus A.; et al. (2005)
Journal of Cardiovascular Magnetic Resonance
Altered Myocardial Motion Pattern in Fabry Patients Assessed with CMR-Tagging
Rutz, Andrea K.; Juli, Christoph F.; Ryf, Salome; et al. (2007)
Journal of Cardiovascular Magnetic Resonance
Oral Administration of 17β-Estradiol Over 3 Months Without Progestin Co-Administration Does Not Improve Coronary Flow Reserve in Post-Menopausal Women: A Randomized Placebo-Controlled Cross-Over CMR Study
Schwitter, Juerg; Kozerke, Sebastian; Bremerich, Jens; et al. (2007)
Journal of Cardiovascular Magnetic Resonance
Detection of coronary stenoses with contrast enhanced, three-dimensional free breathing coronary MR angiography using the gadolinium-based intravascular contrast agent gadocoletic acid (B-22956)
Paetsch, Ingo; Jahnke, Cosima; Barkhausen, Jörg; et al. (2006)
Journal of Cardiovascular Magnetic Resonance

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Journal: Journal of Cardiovascular Magnetic Resonance

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