Journal: Nature Materials

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Abbreviation

Nat. Mater.

Publisher

Nature

Journal Volumes

ISSN

1476-1122
1476-4660

Description

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Publications 1 - 10 of 125
  • Organic electronics
    Item type: Journal Article
    Stingelin, Natalie (2009)
    Nature Materials
  • Gensbittel, Valentin; Yesilata, Zeynep; Bochler, Louis; et al. (2026)
    Nature Materials
    Metastases arise from a multistep process during which tumour cells face several microenvironmental mechanical challenges, which influence metastatic success. However, how circulating tumour cells (CTCs) adapt their mechanics to such microenvironments is not fully understood. Here we report that the deformability of CTCs affects their haematogenous dissemination and identify mechanical phenotypes that favour metastatic extravasation. Combining intravital microscopy with CTC-mimicking elastic beads, mechanical tuning in tumour lines and profiling of tumour-patient-derived cells, we demonstrate that the inherent mechanical properties of circulating objects dictate their ability to enter constraining vessels. We identify cellular viscosity as a rheostat of CTC circulation and arrest, and show that cellular viscosity is crucial for efficient extravasation. Moreover, we find that mechanical properties that favour extravasation and subsequent metastatic outgrowth can be opposite. Altogether, our results establish CTC viscosity as a key biomechanical parameter that shapes several steps of metastasis.
  • Moll, Philip J.W.; Puzniak, Roman; Balakirev, Fedor; et al. (2010)
    Nature Materials
  • Khaliullin, Rustam Z.; Eshet, Hagai; Kühne, Thomas D.; et al. (2011)
    Nature Materials
  • Oxidation-responsive polymeric vesicles
    Item type: Journal Article
    Napoli, Alessandro; Valentini, Massimiliano; Tirelli, Nicola; et al. (2004)
    Nature Materials
  • Fittipaldi, Maria; Cini, Alberto; Annino, Giuseppe; et al. (2019)
    Nature Materials
  • Gradauskaite, Elzbieta; Meier, Quintin N.; Gray, Natascha; et al. (2023)
    Nature Materials
    Material surfaces encompass structural and chemical discontinuities that often lead to the loss of the property of interest in so-called dead layers. It is particularly problematic in nanoscale oxide electronics, where the integration of strongly correlated materials into devices is obstructed by the thickness threshold required for the emergence of their functionality. Here we report the stabilization of ultrathin out-of-plane ferroelectricity in oxide heterostructures through the design of an artificial flux-closure architecture. Inserting an in-plane-polarized ferroelectric epitaxial buffer provides the continuity of polarization at the interface; despite its insulating nature, we observe the emergence of polarization in our out-of-plane-polarized model of ferroelectric BaTiO₃ from the very first unit cell. In BiFeO₃, the flux-closure approach stabilizes a 251° domain wall. Its unusual chirality is probably associated with the ferroelectric analogue to the Dzyaloshinskii–Moriya interaction. We, thus, see that in an adaptively engineered geometry, the depolarizing-field-screening properties of an insulator can even surpass those of a metal and be a source of functionality. This could be a useful insight on the road towards the next generation of oxide electronics.
  • Serrano, Giulia; Poggini, Lorenzo; Briganti, Matteo; et al. (2020)
    Nature Materials
  • Yang, Chun; Tibbitt, Mark W.; Basta, Lena; et al. (2014)
    Nature Materials
  • Delteil, Aymeric; Fink, Thomas; Schade, Anne; et al. (2019)
    Nature Materials
    Cavity–polaritons in semiconductor microstructures have emerged as a promising system for exploring non-equilibrium dynamics of many-body systems. Key advances in this field, including the observation of polariton condensation, superfluidity, realization of topological photonic bands, and dissipative phase transitions, generically allow for a description based on a mean-field Gross–Pitaevskii formalism. Observation of polariton intensity squeezing and decoherence of a polarization entangled photon pair by a polariton condensate, on the other hand, demonstrate quantum effects that show up at high polariton occupancy. Going beyond and into the regime of strongly correlated polaritons requires the observation of a photon blockade effect where interactions are strong enough to suppress double occupancy of a photonic lattice site. Here, we report evidence of quantum correlations between polaritons spatially confined in a fibre cavity. Photon correlation measurements show that careful tuning of the coupled system can lead to a modest reduction of simultaneous two-polariton generation probability by 5%. Concurrently, our experiments allow us to measure the polariton interaction strength, thereby resolving the controversy stemming from recent experimental reports. Our findings constitute an essential step towards the realization of strongly interacting photonic systems.
Publications 1 - 10 of 125