Journal: Annals of the New York Academy of Sciences

Abbreviation

Ann. N.Y. Acad. Sci. IS

Publisher

Wiley

Journal Volumes

ISSN

0077-8923

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Publications 1 - 10 of 11
  • Long-term microbiota and virome in a Zürich patient after fecal transplantation against Clostridium difficile infection
    Item type: Journal Article
    Broecker, Felix; Klumpp, Jochen; Moelling, Karin (2016)
    Annals of the New York Academy of Sciences
  • Historical weather data for climate risk assessment
    Item type: Journal Article
    Brönnimann, Stefan; Martius, Olivia; Rohr, Christian; et al. (2019)
    Annals of the New York Academy of Sciences
  • Eye-head coordination during free exploration in human and cat
    Item type: Journal Article
    Einhäuser, Wolfgang; Moeller, Gudrun U.; Schumann, Frank; et al. (2009)
    Annals of the New York Academy of Sciences
  • Land-atmospheric feedbacks during droughts and heatwaves: state of the science and current challenges
    Item type: Journal Article
    Miralles, Diego G.; Gentine, Pierre; Seneviratne, Sonia I.; et al. (2019)
    Annals of the New York Academy of Sciences
    Droughts and heatwaves cause agricultural loss, forest mortality, and drinking water scarcity, especially when they occur simultaneously as combined events. Their predicted increase in recurrence and intensity poses serious threats to future food security. Still today, the knowledge of how droughts and heatwaves start and evolve remains limited, and so does our understanding of how climate change may affect them. Droughts and heatwaves have been suggested to intensify and propagate via land–atmosphere feedbacks. However, a global capacity to observe these processes is still lacking, and climate and forecast models are immature when it comes to representing the influences of land on temperature and rainfall. Key open questions remain in our goal to uncover the real importance of these feedbacks: What is the impact of the extreme meteorological conditions on ecosystem evaporation? How do these anomalies regulate the atmospheric boundary layer state (event self‐intensification) and contribute to the inflow of heat and moisture to other regions (event self‐propagation)? Can this knowledge on the role of land feedbacks, when available, be exploited to develop geo‐engineering mitigation strategies that prevent these events from aggravating during their early stages? The goal of our perspective is not to present a convincing answer to these questions, but to assess the scientific progress to date, while highlighting new and innovative avenues to keep advancing our understanding in the future.
  • Anti-Nogo on the go
    Item type: Journal Article
    Zörner, Björn; Schwab, Martin E. (2010)
    Annals of the New York Academy of Sciences
  • Pitfalls and requirements in quantifying asymmetric mitotic segregation
    Item type: Journal Article
    Loeffler, Dirk; Schneiter, Florin; Schroeder, Timm (2020)
    Annals of the New York Academy of Sciences
  • Excess iodine intake: sources, assessment, and effects on thyroid function
    Item type: Journal Article
    Farebrother, Jessica; Zimmermann, Michael B.; Andersson, Maria (2019)
    Annals of the New York Academy of Sciences
  • Neuroautonomic activity evidences parturition as a complex and integrated neuro-immune-endocrine process
    Item type: Review Article
    Reyes-Lagos, Jose J.; Ledesma-Ramirez, Claudia I.; Pliego-Carrillo, Adriana C.; et al. (2019)
    Annals of the New York Academy of Sciences
  • Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
    Item type: Journal Article
    Cable, Jennifer; Weber-Ban, Eilika; Clausen, Tim; et al. (2022)
    Annals of the New York Academy of Sciences
    Targeted protein degradation is critical for proper cellular function and development. Protein degradation pathways, such as the ubiquitin proteasomes system, autophagy, and endosome-lysosome pathway, must be tightly regulated to ensure proper elimination of misfolded and aggregated proteins and regulate changing protein levels during cellular differentiation, while ensuring that normal proteins remain unscathed. Protein degradation pathways have also garnered interest as a means to selectively eliminate target proteins that may be difficult to inhibit via other mechanisms. On June 7 and 8, 2021, several experts in protein degradation pathways met virtually for the Keystone eSymposium "Targeting protein degradation: from small molecules to complex organelles." The event brought together researchers working in different protein degradation pathways in an effort to begin to develop a holistic, integrated vision of protein degradation that incorporates all the major pathways to understand how changes in them can lead to disease pathology and, alternatively, how they can be leveraged for novel therapeutics.
  • Single cell biology-a Keystone Symposia report
    Item type: Journal Article
    Cable, Jennifer; Elowitz, Michael B.; Domingos, Ana I.; et al. (2021)
    Annals of the New York Academy of Sciences
    Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer picture of the variation among and between different cell types. New techniques are beginning to unravel how differences in cell state-transcriptional, epigenetic, and other characteristics-can lead to different cell fates among genetically identical cells, which underlies complex processes such as embryonic development, drug resistance, response to injury, and cellular reprogramming. Single cell technologies also pose significant challenges relating to processing and analyzing vast amounts of data collected. To realize the potential of single cell technologies, new computational approaches are needed. On March 17-19, 2021, experts in single cell biology met virtually for the Keystone eSymposium "Single Cell Biology" to discuss advances both in single cell applications and technologies.
Publications 1 - 10 of 11