Journal: Medical Engineering & Physics

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Abbreviation

Med. eng. phys.

Publisher

Elsevier

Journal Volumes

ISSN

1350-4533
1873-4030

Description

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Publications 1 - 10 of 34
  • Samaras , Georgios F.; Dischl , Vincent; Fung , Anita; et al. (2025)
    Medical Engineering & Physics
    In this study, we present a comprehensive numerical model to simulate the injection of hydrogel into femurs. The model is designed to capture the complex interactions between the hydrogel rheological properties and the biomechanical environment of the femur. The coupled mechanical-flow formulation, based on the Theory of Porous Media, is implemented in an open source Abaqus UEL subroutine, where displacements, pressure and saturation are the unknowns. The rheological properties of the hydrogel were calibrated against experimental augmentations in three femurs and the calibrated model was then applied to three different femurs where the hydrogel patterns were compared to experimental data. Furthermore, the simulations demonstrated the effect of injection flow rate and heterogeneous permeability on the hydrogel patterns and quantified the trabecular matrix's solid strains developed during the injection process. The simulations captured well the volume distribution with an average dice coefficient of 0.75 for the three tested specimens. In addition, the calculated solid strains were below the tensile yield limit for the tested flow rate range. A description of the constitutive equations and the implementation into an Abaqus user element subroutine is provided. Overall, our modeling methodology provides a computational tool that can be used to more accurately model bone augmentation and furthermore plan more safely the treatment of osteoporotic patients.
  • Schmid Daners, Marianne; Wullschleger, Luc; Derler, Siegfried; et al. (2008)
    Medical Engineering & Physics
  • Müller, Ralph; Rüegsegger, P. (1995)
    Medical Engineering & Physics
  • Cutrone, Annarita; Sergi, Pier Nicola; Bossi, Silvia; et al. (2011)
    Medical Engineering & Physics
  • Schellenberg, Florian; Taylor, William R.; Trepczynski, Adam; et al. (2018)
    Medical Engineering & Physics
    Standard musculoskeletal simulation tools now offer widespread access to internal loading conditions for use in improving rehabilitation concepts or training programmes. However, despite broad reliance on their outcome, the accuracy of such loading estimations, specifically in deep knee flexion, remains generally unknown. The aim of this study was to evaluate the error of tibio-femoral joint contact force (JCF) calculations using musculoskeletal simulation compared to in vivo measured JCFs in subjects with instrumented total knee endoprostheses during squat exercises. Using the early but common “Gait2392_simbody” (OpenSim) scaled musculoskeletal models, tibio-femoral JCFs were calculated in 6 subjects for 5 repetitions of squats. Tibio-femoral JCFs of 0.8–3.2 times bodyweight (BW) were measured. While the musculoskeletal simulations underestimated the measured knee JCFs at low flexion angles, an average error of less than 20% was achieved between approximately 25°–60° knee flexion. With an average error that behaved almost linearly with knee flexion angle, an overestimation of approximately 60% was observed at deep flexion (ca. 80°), with an absolute maximum error of ca. 1.9BW. Our data indicate that loading estimations from early musculoskeletal gait models at both high and low knee joint flexion angles should be interpreted carefully.
  • Derler, Siegfried; Spierings, Adriaan B.; Schmitt, K.-U. (2005)
    Medical Engineering & Physics
  • Basler, S.E.; Traxler, J.; Müller, Ralph; et al. (2013)
    Medical Engineering & Physics
  • Helgason, B.; Gilchrist, S.; Ariza, O.; et al. (2014)
    Medical Engineering & Physics
  • Enns-Bray, William S.; Ariza, O.; Gilchrist, S.; et al. (2016)
    Medical Engineering & Physics
  • Towards understanding knee joint laxity
    Item type: Journal Article
    Moewis, P.; Boeth, H.; Heller, M.O.; et al. (2014)
    Medical Engineering & Physics
Publications 1 - 10 of 34