Nanoscale

Journal: Nanoscale

Publisher

Royal Society of Chemistry

ISSN

2040-3364
2040-3372

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Publications 1 - 10 of 204

Redox-controlled conductance of polyoxometalate molecular junctions
Huez, Cécile; Guérin, David; Lenfant, Stéphane; et al. (2022)
Nanoscale
We demonstrate the reversible in situ photoreduction of molecular junctions of a phosphomolybdate [PMo12O40](3-) monolayer self-assembled on flat gold electrodes, connected by the tip of a conductive atomic force microscope. The conductance of the one electron reduced [PMo12O40](4-) molecular junction is increased by similar to 10, and this open-shell state is stable in the junction in air at room temperature. The analysis of a large current-voltage dataset by unsupervised machine learning and clustering algorithms reveals that the electron transport in the pristine phosphomolybdate junctions leads to symmetric current-voltage curves, controlled by the lowest unoccupied molecular orbital (LUMO) at 0.6-0.7 eV above the Fermi energy with similar to 25% of the junctions having a better electronic coupling to the electrodes than the main part of the dataset. This analysis also shows that a small fraction (similar to 18% of the dataset) of the molecules is already reduced. The UV light in situ photoreduced phosphomolybdate junctions systematically feature slightly asymmetric current-voltage behaviors, which is ascribed to the electron transport mediated by the single occupied molecular orbital (SOMO) nearly at resonance with the Fermi energy of the electrodes and by a closely located single unoccupied molecular orbital (SUMO) at similar to 0.3 eV above the SOMO with a weak electronic coupling to the electrodes (similar to 50% of the dataset) or at similar to 0.4 eV but with a better electrode coupling (similar to 50% of the dataset). These results shed light on the electronic properties of reversible switchable redox polyoxometalates, a key point for potential applications in nanoelectronic devices.
Novel electrospun chitosan/PEO membranes for more predictive nanoparticle transport studies at biological barriers
Furer, Lea A.; Abad, Ángela Díaz; Manser, Pius; et al. (2022)
Nanoscale
The design of safe and effective nanoparticles (NPs) for commercial and medical applications requires a profound understanding of NP translocation and effects at biological barriers. To gain mechanistic insights, physiologically relevant and accurate human in vitro biobarrier models are indispensable. However, current transfer models largely rely on artificial porous polymer membranes for the cultivation of cells, which do not provide a close mimic of the natural basal membrane and intrinsically provide limited permeability for NPs. In this study, electrospinning is exploited to develop thin chitosan/polyethylene oxide (PEO) membranes with a high porosity and nanofibrous morphology for more predictive NP transfer studies. The nanofiber membranes allow the cultivation of a tight and functional placental monolayer (BeWo trophoblasts). Translocation studies with differently sized molecules and NPs (Na-fluorescein; 40 kDa FITC-Dextran; 25 nm PMMA; 70, 180 and 520 nm polystyrene NPs) across empty and cell containing membranes reveal a considerably enhanced permeability compared to commercial microporous membranes. Importantly, the transfer data of NPs is highly similar to data from ex vivo perfusion studies of intact human placental tissue. Therefore, the newly developed membranes may decisively contribute to establish physiologically relevant in vitro biobarrier transfer models with superior permeability for a wide range of molecules and particles.
Chemical modification of graphene characterized by Raman and transport experiments
Koehler, Fabian M.; Jacobsen, Arnhild; Ihn, Thomas M.; et al. (2012)
Nanoscale
Advanced multiresponsive comploids
Crassous, Jérôme J.; Mihut, Adriana M.; Dietsch, Hervé; et al. (2014)
Nanoscale
Yolk-shell-type CaO-based sorbents for CO2 capture: assessing the role of nanostructuring for the stabilization of the cyclic CO2 uptake
Krödel, Maximilian; Oing, Alexander; Negele, Jan; et al. (2022)
Nanoscale
Beating-wave analysis of small-angle X-ray scattering of unilamellar liposomes loaded with model drug Benzocaine
Baraldi, Laura; Alfarano, Serena R.; Sousa, Flávia; et al. (2025)
Nanoscale
A robust mathematical model was developed to characterize the liposomal bilayer via small-angle X-ray scattering (SAXS). The model was tested on four liposome formulations having the same excipients but different loaded drugs, demonstrating high accuracy in drawing the electron density profiles, highlighting their differences.
Additive manufacturing of Zn with submicron resolution and its conversion into Zn/ZnO core-shell structures
Nydegger, Mirco; Pruska, Adam; Galinski, Henning; et al. (2022)
Nanoscale
Electrohydrodynamic redox 3D printing (EHD-RP) is an additive manufacturing (AM) technique with submicron resolution and multi-metal capabilities, offering the possibility to switch chemistry during deposition “on-the-fly”. Despite the potential for synthesizing a large range of metals by electrochemical small-scale AM techniques, to date, only Cu and Ag have been reproducibly deposited by EHD-RP. Here, we extend the materials palette available to EHD-RP by using aqueous solvents instead of organic solvents, as used previously. We demonstrate deposition of Cu and Zn from sacrificial anodes immersed in acidic aqueous solvents. Mass spectrometry indicates that the choice of the solvent is important to the deposition of pure Zn. Additionally, we show that the deposited Zn structures, 250 nm in width, can be partially converted into semiconducting ZnO structures by oxidation at 325 °C in air.
3D hierarchically porous Cu–BiOCl nanocomposite films: one-step electrochemical synthesis, structural characterization and nanomechanical and photoluminescent properties
Guerrero, Miguel; Pané, Salvador; Nelson, Bradley J.; et al. (2013)
Nanoscale
A rapid and specific antimicrobial resistance detection of Escherichia coli via magnetic nanoclusters
Pan, Fei; Altenried, Stefanie; Scheibler, Subas; et al. (2024)
Nanoscale
Drinking water contamination, often caused by bacteria, leads to substantial numbers of diarrhea deaths each year, especially in developing regions. Human urine as a source of fertilizer, when handled improperly, can contaminate drinking water. One dominant bacterial pathogen in urine is Escherichia coli, which can trigger serious waterborne/foodborne diseases. Considering the prevalence of the multi-drug resistant extended-spectrum beta-lactamase (ESBL) producing E. coli, a rapid detection method for resistance is highly desired. In this work, we developed a method for quick identification of E. coli and, at the same time, capable of removal of general bacterial pathogens from human urine. A specific peptide GRHIFWRRGGGHKVAPR, reported to have a strong affinity to E. coli, was utilized to modify the PEGylated magnetic nanoclusters, resulting in a specific capture and enrichment of E. coli from the bacteria-spiked artificial urine. Subsequently, a novel luminescent probe was applied to rapidly identify the antimicrobial resistance of the collected E. coli within 30 min. These functionalized magnetic nanoclusters demonstrate a promising prospect to rapidly detect ESBL E. coli in urine and contribute to reducing drinking water contamination.
Biodegradable zwitterionic nanoparticles with tunable UCST-type phase separation under physiological conditions
Sponchioni, Mattia; Rodrigues Bassam, Paola; Moscatelli, Davide; et al. (2019)
Nanoscale

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Journal: Nanoscale

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