Biomedical Microdevices

Journal: Biomedical Microdevices

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Springer

ISSN

1387-2176
1572-8781

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Publications 1 - 10 of 15

Superparamagnetic microrobots
Suter, Marcel; Zhang, Li; Siringil, Erdem C.; et al. (2013)
Biomedical Microdevices
Measuring localized viscoelasticity of the vitreous body using intraocular microprobes
Pokki, Juho; Ergeneman, Olgac; Sevim, Semih; et al. (2015)
Biomedical Microdevices
Vitrectomy is a standard ophthalmic procedure to remove the vitreous body from the eye. The biomechanics of the vitreous affects its duration (by changing the removal rate) and the mechanical forces transmitted via the vitreous on the surrounding tissues during the procedure. Biomechanical characterization of the vitreous is essential for optimizing the design and control of instruments that operate within the vitreous for improved precision, safety, and efficacy. The measurements are carried out using a magnetic microprobe inserted into the vitreous, a method known as magnetic microrheology. The location of the probe is tracked by a microscope/camera while magnetic forces are exerted wirelessly by applied magnetic fields. In this work, in vitro artificial vitreous, ex vivo human vitreous and ex vivo porcine vitreous were characterized. In addition, in vivo rabbit measurements were performed using a suturelessly injected probe. Measurements indicate that viscoelasticity parameters of the ex vivo human vitreous are an order of magnitude different from those of the ex vivo porcine vitreous. The in vivo intra-operative measurements show typical viscoelastic behavior of the vitreous with a lower compliance than the ex vivo measurements. The results of the magnetic microrheology measurements were validated with those obtained by a standard atomic force microscopy (AFM) method and in vitro artificial vitreous. This method allows minimally-invasive characterization of localized mechanical properties of the vitreous in vitro, ex vivo, and in vivo. A better understanding of the characteristics of the vitreous can lead to improvements in treatments concerning vitreal manipulation such as vitrectomy.
Stacks of Microfabricated Structures as Scaffolds for Cell Culture and Tissue Engineering
Folch, Albert; Mezzour, Sonia; Düring, Michael; et al. (2000)
Biomedical Microdevices
Microfluidics/CMOS orthogonal capabilities for cell biology
Linder, Vincent; Koster, Sander; Franks, Wendy; et al. (2006)
Biomedical Microdevices
Electrochemically switchable platform for the micro-patterning and release of heterotypic cell sheets
Guillaume-Gentil, Orane; Gabi, Michael; Zenobi-Wong, Marcy; et al. (2011)
Biomedical Microdevices
Porous polysulfone coatings for enhanced drug delivery
Sivaraman, Kartik M.; Kellenberger, Christoph; Pané, Salvador; et al. (2012)
Biomedical Microdevices
MRI driven magnetic microswimmers
Kósa, Gábor; Jakab, Péter; Székely, Gábor; et al. (2012)
Biomedical Microdevices
Development, manufacturing and application of double-sided flexible implantable microelectrodes
Poppendieck, Wigand; Sossalla, Adam; Krob, Marc-Olivier; et al. (2014)
Biomedical Microdevices
A novel method for assessing adherent single-cell stiffness in tension
Bartalena, Guido; Grieder, Reto; Sharma, Ram I.; et al. (2011)
Biomedical Microdevices
Immuno-gold silver staining assays on capillary-driven microfluidics for the detection of malaria antigens
Pham, Ngoc M.; Rusch, Sebastian; Temiz, Yuksel; et al. (2019)
Biomedical Microdevices

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Journal: Biomedical Microdevices

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