A Human-Scale Clinically-Ready Electromagnetic Navigation System for Magnetically-Responsive Biomaterials and Medical Devices


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Date

2024-08-01

Publication Type

Journal Article

ETH Bibliography

yes

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Abstract

Magnetic navigation systems are used to precisely manipulate magnetically responsive materials enabling the realization of new minimally invasive procedures using magnetic medical devices. Their widespread applicability has been constrained by high infrastructure demands and costs. we report on a portable electromagnetic navigation system, the Navion, which is capable of generating a large magnetic field over a large workspace. The system is easy to install in hospital operating rooms and transportable through healthcare facilities, aiding in the widespread adoption of magnetically responsive medical devices. First, we introduce our design and implementation approach for the system and characterize its performance. Next, we demonstrate in vitro navigation of different microrobot structures using magnetic field gradients and rotating magnetic fields. Spherical permanent magnets, electroplated cylindrical microrobots, microparticle swarms, and magnetic composite bacteria-inspired helical structures are investigated. we also demonstrate the navigation of magnetic catheters in two challenging endovascular tasks: (1) an angiography procedure and (2) deep navigation within the circle of Willis. Catheter navigation is demonstrated in a porcine model in vivo to perform an angiography under magnetic guidance.

Publication status

published

Editor

Book title

Volume

36 (31)

Pages / Article No.

2310701

Publisher

Wiley-VCH

Event

Edition / version

Methods

Software

Geographic location

Date collected

Date created

Subject

Electromagnetic navigation systems; remote magnetic navigation; minimally invasive surgery; in vivo; microrobot; particle swarm; ABF

Organisational unit

03627 - Nelson, Bradley J. / Nelson, Bradley J. check_circle
08705 - Gruppe Pané Vidal check_circle

Notes

Funding

952152 - MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutic agents in any vascular rEgion of the body (EC)
743217 - Soft Micro Robotics (EC)
185039 - Arbeitstitel "Soft Magnetic Robots: Modeling, Design and Control of Magnetically Guided Continuum Manipulators" (SNF)
180861 - A Submillimeter Minimally Invasive System for Cardiac Arrhythmia Ablations (SNF)

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