A functionalized polydimethyl siloxane chip for solvent-free, temperature actuated solid phase extraction
METADATA ONLY
Author / Producer
Date
2015
Publication Type
Other Conference Item
ETH Bibliography
yes
Citations
Altmetric
METADATA ONLY
Data
Rights / License
Abstract
This paper introduces a new approach for solvent-free solid phase extraction on a microfluidic chip. As a proof of concept study, we developed PDMS devices with pillar arrays to support the sorbent. Traditional reverse phase sorbent material was replaced by a thermo-responsive polymer, poly(Nisopropylacrylamide), that enables the extraction and release of biomolecules in aqueous media by varying the temperature. Two functionalization methods of the PDMS surface were investigated. This study is the starting point for future work in the field of environmental analysis involving
immunodetection methods.
Permanent link
Publication status
published
External links
Editor
Book title
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)
Journal / series
Volume
Pages / Article No.
1990 - 1992
Publisher
Chemical and Biological Microsystems Society
Event
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2015)
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
Microfluidics; PDMS; PNIPAAm; Solid phase extraction; Thermo-responsive polymer
Organisational unit
03807 - Dittrich, Petra S. / Dittrich, Petra S.
Notes
Poster abstract. Poster presentation on October 28, 2015.