A mouse plasma peptide atlas as a resource for disease proteomics
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Date
2008
Publication Type
Journal Article
ETH Bibliography
yes
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Abstract
We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 proteins are estimated to span a 7 logarithmic range of abundance in plasma. A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis.
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published
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Journal / series
Volume
9 (6)
Pages / Article No.
Publisher
BioMed Central
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Edition / version
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Date collected
Date created
Subject
Epidermal Growth Factor Receptor; Ingenuity Pathway Analysis; Mouse Plasma; International Protein Index; Plasma Proteome
Organisational unit
03663 - Aebersold, Rudolf (emeritus) / Aebersold, Rudolf (emeritus)