Using an active phase cancellation and multipair design for in-vivo focal temporal interference electrical brain stimulation
Towards focal non-invasive electrical brain stimulation
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Date
2023
Publication Type
Conference Poster
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yes
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Abstract
Temporal Interference Stimulation (TI) (1) represents a novel technique for deep brain stimulation, aiming to integrate the depth characteristic of conventional deep brain stimulation protocols with the non-invasive nature of transcranial electric and magnetic stimulations (tACS and TMS). Recent publications in both mice and humans explicitly demonstrated that deep brain areas including the hippocampus and the striatum could be stimulated using TI (2, 3). However, whereas TI stimulation is set to be focused on a specific region of interest (ROI), other off-target areas may still be stimulated due to the field propagation. This is a major concern when TI is employed at high stimulation amplitudes, as off-target stimulations have a potential to cause unwanted side effects such as epileptic convulsions (2).
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published
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Publisher
ETH Zurich, Department of Health Sciences and Technology
Event
2023 Annual Meeting of the Swiss Society for Neuroscience
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Subject
Neuroscience; Engineering; fMRI BOLD; brain stimulation; Animals; Temporal Interferece; Multipair Temporal Interference
Organisational unit
09648 - Razansky, Daniel / Razansky, Daniel
02202 - Zentrum für Neurowissenschaften / Neuroscience Center Zurich
Notes
Illustrations were created with Biorender.com
Funding
ETH-25 18-2 - Artificially regulating reward processing via non-invasive deep brain stimulation (ART-REWARD) (ETHZ)
Related publications and datasets
Is supplement to: https://doi.org/10.3929/ethz-b-000628288