Four-dimensional in vivo X-ray microscopy with projection-guided gating
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Author / Producer
Date
2015-03-12
Publication Type
Journal Article
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yes
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Abstract
Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve the spatiotemporal resolution by an order of magnitude over previous studies. We demonstrate our method by visualizing 20 three-dimensional snapshots through the 150 Hz oscillations of the blowfly flight motor.
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published
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Journal / series
Volume
5
Pages / Article No.
8727
Publisher
Nature
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Subject
Imaging techniques; Phase-contrast microscopy; X-ray Tomography
Organisational unit
03817 - Stampanoni, Marco F.M. / Stampanoni, Marco F.M.