Electrochemical Paper-Based Microfluidics: Harnessing Capillary Flow for Advanced Diagnostics
OPEN ACCESS
Loading...
Author / Producer
Date
2024-09-19
Publication Type
Review Article
ETH Bibliography
yes
Citations
Altmetric
OPEN ACCESS
Data
Abstract
Electrochemical paper-based microfluidics has attracted much attention due to the promise of transforming point-of-care diagnostics by facilitating quantitative analysis with low-cost and portable analyzers. Such devices harness capillary flow to transport samples and reagents, enabling bioassays to be executed passively. Despite exciting demonstrations of capillary-driven electrochemical tests, conventional methods for fabricating electrodes on paper impede capillary flow, limit fluidic pathways, and constrain accessible device architectures. This account reviews recent developments in paper-based electroanalytical devices and offers perspective by revisiting key milestones in lateral flow tests and paper-based microfluidics engineering. The study highlights the benefits associated with electrochemical sensing and discusses how the detection modality can be leveraged to unlock novel functionalities. Particular focus is given to electrofluidic platforms that embed electrodes into paper for enhanced biosensing applications. Together, these innovations pave the way for diagnostic technologies that offer portability, quantitative analysis, and seamless integration with digital healthcare, all without compromising the simplicity of commercially available rapid diagnostic tests.
Permanent link
Publication status
published
External links
Editor
Book title
Journal / series
Volume
20 (38)
Pages / Article No.
2401148
Publisher
Wiley-VCH
Event
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
electroanalytical devices; electrochemical sensors; laser-induced graphene; paper microfluidics; point-of-care diagnostics; printed electronics
Organisational unit
03914 - deMello, Andrew / deMello, Andrew
Notes
Funding
840232 - Automated microfluidic phage display through non-fouling droplet-based technologies (EC)
178944 - Engineering Colloidal Perovskite Quantum Well Light Emitting Technology (SNF)
178944 - Engineering Colloidal Perovskite Quantum Well Light Emitting Technology (SNF)