Structural genomic variation leads to genetic differentiation in Lake Tanganyika's sardines


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Date

2020-09

Publication Type

Journal Article

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Abstract

Identifying patterns in genetic structure and the genetic basis of ecological adaptation is a core goal of evolutionary biology and can inform the management and conservation of species that are vulnerable to population declines exacerbated by climate change. We used reduced-representation genomic sequencing methods to gain a better understanding of genetic structure among and within populations of Lake Tanganyika's two sardine species,Limnothrissa miodonandStolothrissa tanganicae. Samples of these ecologically and economically important species were collected across the length of Lake Tanganyika, as well as from nearby Lake Kivu, whereL. miodonwas introduced in 1959. Our results reveal differentiation within bothS. tanganicaeandL. miodonthat is not explained by geography. Instead, this genetic differentiation is due to the presence of large sex-specific regions in the genomes of both species, but involving different polymorphic sites in each species. Our results therefore indicate rapidly evolving XY sex determination in the two species. Additionally, we found evidence of a large chromosomal rearrangement inL. miodon, creating two homokaryotypes and one heterokaryotype. We found all karyotypes throughout Lake Tanganyika, but the frequencies vary along a north-south gradient and differ substantially in the introduced Lake Kivu population. We do not find evidence for significant isolation by distance, even over the hundreds of kilometres covered by our sampling, but we do find shallow population structure.

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published

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Volume

29 (17)

Pages / Article No.

3277 - 3298

Publisher

Wiley

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Subject

chromosomal rearrangement; Lake Tanganyika; Limnothrissa miodon; sex-specific region; Stolothrissa tanganicae

Organisational unit

03328 - Wehrli, Bernhard (emeritus) / Wehrli, Bernhard (emeritus) check_circle

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