How to Take Autophagy and Endocytosis Up a Notch
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Date
2014-04-22
Publication Type
Journal Article
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yes
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Abstract
The interconnection of the endocytic and autophagosomal trafficking routes has been recognized more than two decades ago with both pathways using a set of identical effector proteins and sharing the same ultimate lysosomal destination. More recent data sheds light onto how other pathways are intertwined into this network, and how degradation via the endosomal/autophagosomal system may affect signaling pathways in multicellular organisms. Here, we briefly review the common features of autophagy and endocytosis and discuss how other players enter this mix with particular respect to the Notch signaling pathway.
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published
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Journal / series
Volume
2014
Pages / Article No.
960803
Publisher
Hindawi