Physical stability of peptide pharmaceuticals
aggregation and conformational changes of human calcitonin (hCT) in aqueous solution
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Date
1995
Publication Type
Doctoral Thesis
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published
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Examiner : Merkle, Hans Peter
Examiner : Schurtenberger, Peter
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PROTEINE, POLYPEPTIDE, ENZYME, ENZYMINHIBITOREN, PEPTIDE (PHARMAZIE); ARZNEIMITTELSTABILITÄT + ARZNEIMITTELZERSETZUNG; STRUKTURDYNAMIK, STRUKTUR- UND KONFORMATIONSVERÄNDERUNGEN (BIOMOLEKÜLE); CALCITONIN (HORMONE); WÄSSRIGE LÖSUNGEN + WASSERLÖSLICHKEIT (CHEMIE); PROTEINS, POLYPEPTIDES, ENZYMES, ENZYME INHIBITORS, PEPTIDES (PHARMACY); DRUG STABILITY + DRUG DEGRADATION (PHARMACIE); STRUCTURAL DYNAMICS, STRUCTURAL AND CONFORMATIONAL CHANGES (BIOMOLECULES); CALCITONIN (HORMONES); AQUEOUS SOLUTIONS + WATER SOLUBILITY (CHEMISTRY)
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Diss. Naturwiss. ETH Zürich, Nr. 10989, 1995. Ref.: H. P. Merkle ; Korref.: P. Schurtenberger ; Korref.: T. Arvinte.