High throughput screening for discovery of materials that control stem cell fate
OPEN ACCESS
Author / Producer
Date
2016-08
Publication Type
Journal Article
ETH Bibliography
no
Citations
Altmetric
OPEN ACCESS
Data
Rights / License
Abstract
Insights into the complex stem cell niche have identified the cell–material interface to be a potent regulator of stem cell fate via material properties such as chemistry, topography and stiffness. In light of this, materials scientists have the opportunity to develop bioactive materials for stem cell culture that elicit specific cellular responses. To accelerate materials discovery, high throughput screening platforms have been designed which can rapidly evaluate combinatorial material libraries in two and three-dimensional environments. In this review, we present screening platforms for the discovery of material properties that influence stem cell behavior.
Permanent link
Publication status
published
External links
Editor
Book title
Journal / series
Volume
20 (4)
Pages / Article No.
202 - 211
Publisher
Elsevier
Event
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
Stem cells; Differentiation; Biomaterials; High throughput screening; 3D
Organisational unit
09472 - Tibbitt, Mark / Tibbitt, Mark