Approximate model reductions for combinatorial reaction systems
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Date
2013
Publication Type
Conference Paper
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yes
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Abstract
The paper considers a model reduction technique that is well-suited for biochemical reaction systems giving rise to the assembly of a large number of different molecular species. The reduction is performed by grouping species with common properties, directly from the model specification in terms of a rule-based language. In recent works, general algorithms for the exact reductions of rule-based models were established, but the state space often remains combinatorial. We extend this line of research by introducing approximate reductions, and an error measure which allows us to quantitatively study the effect of approximate model reductions.
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2013 European Control Conference (ECC)
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Pages / Article No.
4172 - 4177
Publisher
IEEE
Event
12th European Control Conference (ECC 2013)
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03883 - Köppl, Heinz W. (SNF-Professur) (ehem.)