jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths
METADATA ONLY
Loading...
Author / Producer
Date
2020-07
Publication Type
Journal Article
ETH Bibliography
yes
Citations
Altmetric
METADATA ONLY
Data
Rights / License
Abstract
Femtosecond lasers at fixed wavelengths above 1,000 nm are powerful, stable and inexpensive, making them promising sources for two-photon microscopy. Biosensors optimized for these wavelengths are needed for both next-generation microscopes and affordable turn-key systems. Here we report jYCaMP1, a yellow variant of the calcium indicator jGCaMP7 that outperforms its parent in mice and flies at excitation wavelengths above 1,000 nm and enables improved two-color calcium imaging with red fluorescent protein-based indicators.
Permanent link
Publication status
published
External links
Editor
Book title
Journal / series
Volume
17 (7)
Pages / Article No.
694 - 697
Publisher
Nature