Multiplexed Point-of-Care Testing - xPOCT
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Author / Producer
Date
2017-08
Publication Type
Review Article
ETH Bibliography
yes
Citations
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OPEN ACCESS
Data
Abstract
Multiplexed point-of-care testing (xPOCT), which is simultaneous on-site detection of different analytes from a single specimen, has recently gained increasing importance for clinical diagnostics, with emerging applications in resource-limited settings (such as in the developing world, in doctors’ offices, or directly at home). Nevertheless, only single-analyte approaches are typically considered as the major paradigm in many reviews of point-of-care testing. Here, we comprehensively review the present diagnostic systems and techniques for xPOCT applications. Different multiplexing technologies (e.g., bead- or array-based systems) are considered along with their detection methods (e.g., electrochemical or optical). We also address the unmet needs and challenges of xPOCT. Finally, we critically summarize the in-field applicability and the future perspectives of the presented approaches.
Permanent link
Publication status
published
External links
Editor
Book title
Journal / series
Volume
35 (8)
Pages / Article No.
728 - 742
Publisher
Elsevier
Event
Edition / version
Methods
Software
Geographic location
Date collected
Date created
Subject
lab-on-a-chip (LOC); microfluidics; multianalyte analysis; multiplexing; on-site testing; point-of-care testing (POCT)
Organisational unit
03807 - Dittrich, Petra S. / Dittrich, Petra S.
Notes
Funding
681587 - Engineering of hybrid cells using lab-on-chip technology (EC)