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Modularity and hormone sensitivity of the Drosophila melangaster insulin receptor/target of rapamycin interaction proteome
(2011)Molecular Systems BiologyGenetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this regulatory system is still poorly characterized in Drosophila. Here, we present the first quantitative study that systematically characterizes ...Journal Article