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Combined burden and functional impact tests for cancer driver discovery using DriverPower
(2020)Nature CommunicationsThe discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutations in coding and non-coding sites within ...Journal Article -
Matrix modeling of energy hub with variable energy efficiencies
(2020)International Journal of Electrical Power & Energy SystemsJournal Article -
Induced fault reactivation by thermal perturbation in enhanced geothermal systems
(2020)GeothermicsJournal Article -
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Consumer responses to novel and unfamiliar foods
(2020)Current Opinion in Food ScienceReview Article -
Strain gradient mediated magnetoelectricity in Fe-Ga/P(VDF-TrFE) multiferroic bilayers integrated on silicon
(2020)Applied Materials TodayThe primary advantage of magnetoelectric heterostructures exhibiting direct magnetoelectric effect is the possibility to induce and modulate the electrical response of the ferroelectric phase directly with an external magnetic field (i.e., wirelessly, without applying electric field). Nevertheless, the magnetoelectric coupling in such heterostructures is commonly limited by substrate clamping which hinders effective strain propagation. ...Journal Article -
A moment and sum-of-squares extension of dual dynamic programming with application to nonlinear energy storage problems
(2020)European Journal of Operational ResearchJournal Article -
Spatial and temporal evolution of groundwater arsenic contamination in the Red River delta, Vietnam: Interplay of mobilisation and retardation processes
(2020)Science of the Total EnvironmentGeogenic arsenic (As) contamination of groundwater poses a major threat to global health, particularly in Asia. To mitigate this exposure, groundwater is increasingly extracted from low-As Pleistocene aquifers. This, however, disturbs groundwater flow and potentially draws high-As groundwater into low-As aquifers. Here we report a detailed characterisation of the Van Phuc aquifer in the Red River Delta region, Vietnam, where high-As ...Journal Article -
Unravelling 5 decades of anthropogenic 236U discharge from nuclear reprocessing plants
(2020)Science of the Total EnvironmentMarine biogenic materials such as corals, shells, or seaweed have long been recognized as recorders of environmental conditions. Here, the bivalve Cerastoderma edule is used for the first time as a recorder of past seawater contamination with anthropogenic uranium, specifically 236U. Several studies have employed the authorized radioactive releases, including 236U, from nuclear reprocessing plants in La Hague, France, into the English ...Journal Article -
Combinatorial investigation of Al–Cu intermetallics using small-scale mechanical testing
(2020)Journal of Alloys and CompoundsJournal Article