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Producing plankton classifiers that are robust to dataset shift
(2024)Limnology and Oceanography MethodsModern plankton high-throughput monitoring relies on deep learning classifiers for species recognition in water ecosystems. Despite satisfactory nominal performances, a significant challenge arises from dataset shift, which causes performances to drop during deployment. In our study, we integrate the ZooLake dataset, which consists of dark-field images of lake plankton (Kyathanahally et al. 2021a), with manually annotated images from 10 ...Journal Article -
[<SUP>18</SUP>F]NP3-627, a Candidate PET Imaging Agent Targeting the NLRP3 Inflammasome in the Central Nervous System
(2024)ChemMedChemWe describe the identification of a candidate positron emission tomography (PET) imaging agent for the NLRP3 protein. NLRP3 plays a critical role in the immune system and has proven a difficult target for the development of imaging agents due to its low and cell-specific expression profile. A recently described series of pyridazine-based inhibitors, with improved permeability and brain-penetration properties, was used as a starting point ...Journal Article -
The lives of cells, recorded
(2024)Nature Reviews GeneticsA paradigm for biology is emerging in which cells can be genetically programmed to write their histories into their own genomes. These records can subsequently be read, and the cellular histories reconstructed, which for each cell could include a record of its lineage relationships, extrinsic influences, internal states and physical locations, over time. DNA recording has the potential to transform the way that we study developmental and ...Review Article -
Forest Owner Attitudes Toward Climate-Proof Forest Management in Sweden and the Netherlands-Between Forest Strategies and Practical Measures (oct, 10.1007/s11842-024-09576-0, 2024)
(2024)Small-scale ForestryOther Journal Item -
Quantitative Sizing of Microplastics up to 20 µm using ICP-TOFMS
(2025)Journal of Analytical Atomic SpectrometryA fundamental study of four different sample introduction systems was carried out to evaluate the upper size limit of microplastics measured by inductively coupled plasma-time-of-flight-mass spectrometry (ICP-TOFMS). Three different, certified microplastic samples (PS, PMMA and PVC) within a size range of 3-20 μm in suspension were measured. In this study, no particles larger than 10 μm could be detected using pneumatic nebulization for ...Journal Article -
Correlation of cross-linking as measured by the trans-vinylene index and in vitro wear of polyethylene from various acetabular liner brands
(2024)Bone & Joint ResearchAims Highly cross-linked polyethylene (HXLPE) greatly reduces wear in total hip arthroplasty, compared to conventional polyethylene (CPE). Cross-linking is commonly achieved by irradiation. This study aimed to compare the degree of cross-linking and in vitro wear rates across a cohort of retrieved and unused polyethylene cups/liners from various brands. Methods Polyethylene acetabular cups/liners were collected at one centre from 1 April ...Journal Article -
Gallic and Ellagic Acids Differentially Affect Microbial Community Structures and Methane Emission When Using a Rumen Simulation Technique
(2024)Journal of Agricultural and Food ChemistryDietary tannins can affect rumen microbiota and enteric fermentation to mitigate methane emissions, although such effects have not yet been fully elucidated. We tested two subunits of hydrolyzable tannins named gallic acid (GA) and ellagic acid (EA), alone (75 mg/g DM each) or combined (150 mg/g DM in total), using the Rusitec system. EA and EA+GA treatments decreased methane production, volatile fatty acids, nutrient degradation, relative ...Journal Article -
Impact of climate change on snow avalanche activity in the Swiss Alps
(2024)The CryosphereThe cryosphere in mountain regions is rapidly transforming due to climate change, yet the impact of these changes on snow avalanche activity remains uncertain. Here, we use a snow cover model driven by downscaled climate projections to evaluate future alterations in dry- and wet-snow avalanche occurrences throughout the 21st century in the Swiss Alps. We assess avalanche activity by employing machine learning models trained with observed ...Journal Article -
Backtesting Systemic Risk Forecasts Using Multi-Objective Elicitability
(2024)Journal of Business & Economic StatisticsJournal Article -
The Zero Emissions Commitment and climate stabilization
(2023)Frontiers in ScienceHow do we halt global warming? Reaching net zero carbon dioxide (CO2) emissions is understood to be a key milestone on the path to a safer planet. But how confident are we that when we stop carbon emissions, we also stop global warming? The Zero Emissions Commitment (ZEC) quantifies how much warming or cooling we can expect following a complete cessation of anthropogenic CO2 emissions. To date, the best estimate by the Intergovernmental ...Journal Article