Total Synthesis and SAR Investigations of Natural Products Inhibiting Bacterial RNA Polymerase

Ripostatin B and Tiacumicin B
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Author
Glaus, Florian D.
Date
2015
Type
  • Doctoral Thesis
Rights / license
In Copyright - Non-Commercial Use Permitted
Permanent link
https://doi.org/10.3929/ethz-a-010422569
Publication status
published
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Contributors
Examiner: Altmann, Karl-Heinz
Examiner: Carreira, Erick Moran
Publisher
ETH-Zürich
Subject
PHARMAKODYNAMIK + ARZNEIMITTELWIRKUNG (PHARMAKOLOGIE); MYCOBACTERIUM TUBERCULOSIS (MICROBIOLOGY); MYCOBACTERIUM TUBERCULOSIS (MIKROBIOLOGIE); ANTIBAKTERIELLE ANTIBIOTIKA; ANTIBACTERIAL ANTIBIOTICS; MYXOCOCCALES (MICROBIOLOGY); DRUG DEVELOPMENT + DRUG DESIGN + DRUG DISCOVERY (PHARMACY); MYXOCOCCALES (MIKROBIOLOGIE); ARZNEIMITTELENTWICKLUNG + ARZNEIMITTELDESIGN + ARZNEIMITTELENTDECKUNG; RNA-POLYMERASEN, RNA-NUKLEOTIDYLTRANSFERASEN (ENZYME); STRUCTURE-ACTIVITY RELATION (CHEMISTRY); PHARMACODYNAMICS + DRUG ACTION (PHARMACOLOGY); RNA POLYMERASES, RNA NUCLEOTIDYLTRANSFERASES (ENZYMES); STRUKTUR-AKTIVITÄTSBEZIEHUNG (CHEMIE)
Organisational unit
02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences
03647 - Altmann, Karl-Heinz / Altmann, Karl-Heinz  
02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.
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