Total Synthesis and SAR Investigations of Natural Products Inhibiting Bacterial RNA Polymerase

Ripostatin B and Tiacumicin B
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Author
Glaus, Florian D.
Date
2015
Type
  • Doctoral Thesis
Rights / license
In Copyright - Non-Commercial Use Permitted
Permanent link
https://doi.org/10.3929/ethz-a-010422569
Publication status
published
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Contributors
Supervisor: Altmann, Karl-Heinz
Supervisor: Carreira, Erick Moran
Publisher
ETH-Zürich
Subject
PHARMAKODYNAMIK + ARZNEIMITTELWIRKUNG (PHARMAKOLOGIE); MYCOBACTERIUM TUBERCULOSIS (MICROBIOLOGY); MYCOBACTERIUM TUBERCULOSIS (MIKROBIOLOGIE); ANTIBAKTERIELLE ANTIBIOTIKA; ANTIBACTERIAL ANTIBIOTICS; MYXOCOCCALES (MICROBIOLOGY); DRUG DEVELOPMENT + DRUG DESIGN + DRUG DISCOVERY (PHARMACY); MYXOCOCCALES (MIKROBIOLOGIE); ARZNEIMITTELENTWICKLUNG + ARZNEIMITTELDESIGN + ARZNEIMITTELENTDECKUNG; RNA-POLYMERASEN, RNA-NUKLEOTIDYLTRANSFERASEN (ENZYME); STRUCTURE-ACTIVITY RELATION (CHEMISTRY); PHARMACODYNAMICS + DRUG ACTION (PHARMACOLOGY); RNA POLYMERASES, RNA NUCLEOTIDYLTRANSFERASES (ENZYMES); STRUKTUR-AKTIVITÄTSBEZIEHUNG (CHEMIE)
Organisational unit
02534 - Institut für Pharmazeutische Wissenschaften / Institute of Pharmaceutical Sciences
03647 - Altmann, Karl-Heinz
02020 - Departement Chemie und Angewandte Biowissenschaften / Department of Chemistry and Applied Biosciences
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