Release of copper-amended particles from micronized copper-pressure-treated wood during mechanical abrasion

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Date
2016-11-28Type
- Journal Article
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Cited 19 times in
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Cited 13 times in
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Abstract
Background
We investigated the particles released due to abrasion of wood surfaces pressure-treated with micronized copper azole (MCA) wood preservative and we gathered preliminary data on its in vitro cytotoxicity for lung cells. The data were compared with particles released after abrasion of untreated, water (0% MCA)-pressure-treated, chromated copper (CC)-pressure-treated wood, and varnished wood. Size, morphology, and composition of the released particles were analyzed.
Results
Our results indicate that the abrasion of MCA-pressure-treated wood does not cause an additional release of nanoparticles from the unreacted copper (Cu) carbonate nanoparticles from of the MCA formulation. However, a small amount of released Cu was detected in the nanosized fraction of wood dust, which could penetrate the deep lungs. The acute cytotoxicity studies were performed on a human lung epithelial cell line and human macrophages derived from a monocytic cell line. These cell types are likely to encounter the released wood particles after inhalation.
Conclusions
Our findings indicate that under the experimental conditions chosen, MCA does not pose a specific additional nano-risk, i.e. there is no additional release of nanoparticles and no specific nano-toxicity for lung epithelial cells and macrophages. Show more
Permanent link
https://doi.org/10.3929/ethz-b-000123721Publication status
publishedExternal links
Journal / series
Journal of NanobiotechnologyVolume
Pages / Article No.
Publisher
BioMed CentralSubject
Cytotoxicity; Copper particles; Debris; Exposure; Inhalation; Wood dustMore
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Citations
Cited 19 times in
Web of Science
Cited 13 times in
Scopus
ETH Bibliography
yes
Altmetrics