Particle concentration influences inertial focusing in Multiorifice Flow Fractionation microfluidic devices

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Date
2016-10-26Type
- Journal Article
ETH Bibliography
yes
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Abstract
Multiorifice - Flow - Fractionation (MOFF) devices have been used for the separation of microparticles and cells according to their size and the degree of inertia (i.e. Re number). Herein an additional parameter, particle concentration; is reported to affect the performance of MOFF when the remaining conditions are unchanged. Particularly, at low concentrations focusing occurs efficiently at the center of these devices, while at higher concentrations particles tend to accumulate near the channel walls. This indicates that particle-particle interactions are a key components in the performances of these devices. Show more
Permanent link
https://doi.org/10.3929/ethz-b-000124969Publication status
publishedJournal / series
MattersPages / Article No.
Publisher
ScienceMatters AGSubject
Multiorifice Flow Fractionation; Inertial MicrofluidicsOrganisational unit
03914 - deMello, Andrew / deMello, Andrew
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ETH Bibliography
yes
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