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dc.contributor.author
Stoller, Oliver
dc.contributor.author
de Bruin, Eling D.
dc.contributor.author
Schindelholz, Matthias
dc.contributor.author
Schuster-Amft, Corina
dc.contributor.author
de Bie, Rob A.
dc.contributor.author
Hunt, Kenneth J.
dc.date.accessioned
2017-12-21T14:25:34Z
dc.date.available
2017-06-14T00:35:07Z
dc.date.available
2017-07-12T08:25:11Z
dc.date.available
2017-12-21T14:25:34Z
dc.date.issued
2014-10-11
dc.identifier.issn
1743-0003
dc.identifier.other
10.1186/1743-0003-11-145
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/154833
dc.identifier.doi
10.3929/ethz-a-010336651
dc.description.abstract
Background Exercise capacity is seriously reduced after stroke. While cardiopulmonary assessment and intervention strategies have been validated for the mildly and moderately impaired populations post-stroke, there is a lack of effective concepts for stroke survivors suffering from severe motor limitations. This study investigated the test-retest reliability and repeatability of cardiopulmonary exercise testing (CPET) using feedback-controlled robotics-assisted treadmill exercise (FC-RATE) in severely motor impaired individuals early after stroke. Methods 20 subjects (age 44–84 years, <6 month post-stroke) with severe motor limitations (Functional Ambulatory Classification 0–2) were selected for consecutive constant load testing (CLT) and incremental exercise testing (IET) within a powered exoskeleton, synchronised with a treadmill and a body weight support system. A manual human-in-the-loop feedback system was used to guide individual work rate levels. Outcome variables focussed on standard cardiopulmonary performance parameters. Relative and absolute test-retest reliability were assessed by intraclass correlation coefficients (ICC), standard error of the measurement (SEM), and minimal detectable change (MDC). Mean difference, limits of agreement, and coefficient of variation (CoV) were estimated to assess repeatability. Results Peak performance parameters during IET yielded good to excellent relative reliability: absolute peak oxygen uptake (ICC =0.82), relative peak oxygen uptake (ICC =0.72), peak work rate (ICC =0.91), peak heart rate (ICC =0.80), absolute gas exchange threshold (ICC =0.91), relative gas exchange threshold (ICC =0.88), oxygen cost of work (ICC =0.87), oxygen pulse at peak oxygen uptake (ICC =0.92), ventilation rate versus carbon dioxide output slope (ICC =0.78). For these variables, SEM was 4-13%, MDC 12-36%, and CoV 0.10-0.36. CLT revealed high mean differences and insufficient test-retest reliability for all variables studied. Conclusions This study presents first evidence on reliability and repeatability for CPET in severely motor impaired individuals early after stroke using a feedback-controlled robotics-assisted treadmill. The results demonstrate good to excellent test-retest reliability and appropriate repeatability for the most important peak cardiopulmonary performance parameters. These findings have important implications for the design and implementation of cardiovascular exercise interventions in severely impaired populations. Future research needs to develop advanced control strategies to enable the true limit of functional exercise capacity to be reached and to further assess test-retest reliability and repeatability in larger samples.
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Stroke rehabilitation
en_US
dc.subject
Subacute
en_US
dc.subject
Severe motor impairment
en_US
dc.subject
Robotics-assisted gait training
en_US
dc.subject
Aerobic capacity
en_US
dc.subject
Treadmill exercise
en_US
dc.title
Cardiopulmonary exercise testing early after stroke using feedback-controlled robotics-assisted treadmill exercise: test-retest reliability and repeatability
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2014-10-11
ethz.journal.title
Journal of NeuroEngineering and Rehabilitation
ethz.journal.volume
11
en_US
ethz.journal.abbreviated
J Neuroeng Rehabil
ethz.pages.start
145
en_US
ethz.size
13 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.code.ddc
6 - Technology, medicine and applied sciences::610 - Medical sciences, medicine
en_US
ethz.code.ddc
6 - Technology, medicine and applied sciences::621.3 - Electric engineering
en_US
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02535 - Institut für Bewegungswiss. und Sport / Institut of Human Movement Sc. and Sport::09560 - De Bock, Katrien / De Bock, Katrien::08758 - Trainingslehre / E. de Bruin
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02070 - Dep. Gesundheitswiss. und Technologie / Dep. of Health Sciences and Technology::02535 - Institut für Bewegungswiss. und Sport / Institut of Human Movement Sc. and Sport::09560 - De Bock, Katrien / De Bock, Katrien::08758 - Trainingslehre / E. de Bruin
en_US
ethz.date.deposited
2017-06-14T00:45:45Z
ethz.source
ECOL
ethz.identifier.importid
imp59366b6a4e19330171
ethz.ecolpid
eth:47114
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-12T08:25:18Z
ethz.rosetta.lastUpdated
2018-11-06T06:02:57Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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