Inhibition of oncogenic MAPK signaling in melanoma triggers a SOX2-dependent stemness program to promote adaptive drug resistance

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Author
Flückiger-Mangual, Stefanie
Date
2015
Type
    Doctoral Thesis
Rights / license
In Copyright - Non-Commercial Use Permitted
Permanent link
https://doi.org/10.3929/ethz-a-010596039
Publication status
published
External links
Search print copy at ETH Library
Contributors
Examiner: Krek, Wilhelm
Examiner: Christofori, Gerhard
Examiner: Peter, Matthias
Publisher
ETH Zurich
Subject
MELANOME (PATHOLOGIE); GENETISCHE ASPEKTE VON KREBS (MEDIZINISCHE GENETIK); MITOGEN AKTIVIERTE PROTEINKINASEN (ENZYME); REGULATION DER SIGNALTRANSDUKTION (BIOKOMMUNIKATION); KREBSZELLEN (CYTOPATHOLOGIE); KREBSHEMMENDE ARZNEIMITTEL (PHARMAZIE); ARZNEIMITTELRESISTENZ (PHARMAKOLOGIE); MELANOMATA (PATHOLOGY); GENETIC ASPECTS OF CANCER (MEDICAL GENETICS); MITOGEN ACTIVATED PROTEIN KINASES (ENZYMES); REGULATION OF SIGNAL TRANSDUCTION (BIOCOMMUNICATION); CANCER CELLS (CYTOPATHOLOGY); CARCINOSTATICS + ANTINEOPLASTICS + ONCOSTATICS + CANCER REMEDIES (PHARMACY); DRUG RESISTANCE (PHARMACOLOGY)
Organisational unit
02030 - Dep. Biologie / Dep. of Biology
03630 - Krek, Wilhelm (ehemalig) / Krek, Wilhelm (former)  
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