Inhibition of oncogenic MAPK signaling in melanoma triggers a SOX2-dependent stemness program to promote adaptive drug resistance
dc.contributor.author
Flückiger-Mangual, Stefanie
dc.contributor.supervisor
Krek, Wilhelm
dc.contributor.supervisor
Christofori, Gerhard
dc.contributor.supervisor
Peter, Matthias
dc.date.accessioned
2019-02-25T13:49:42Z
dc.date.available
2017-06-14T04:01:10Z
dc.date.available
2017-08-25T12:40:33Z
dc.date.available
2019-02-25T13:49:42Z
dc.date.issued
2015
dc.identifier.uri
http://hdl.handle.net/20.500.11850/155452
dc.identifier.doi
10.3929/ethz-a-010596039
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
ETH Zurich
en_US
dc.rights.uri
http://rightsstatements.org/page/InC-NC/1.0/
dc.subject
MELANOME (PATHOLOGIE)
en_US
dc.subject
GENETISCHE ASPEKTE VON KREBS (MEDIZINISCHE GENETIK)
en_US
dc.subject
MITOGEN AKTIVIERTE PROTEINKINASEN (ENZYME)
en_US
dc.subject
REGULATION DER SIGNALTRANSDUKTION (BIOKOMMUNIKATION)
en_US
dc.subject
KREBSZELLEN (CYTOPATHOLOGIE)
en_US
dc.subject
KREBSHEMMENDE ARZNEIMITTEL (PHARMAZIE)
en_US
dc.subject
ARZNEIMITTELRESISTENZ (PHARMAKOLOGIE)
en_US
dc.subject
MELANOMATA (PATHOLOGY)
en_US
dc.subject
GENETIC ASPECTS OF CANCER (MEDICAL GENETICS)
en_US
dc.subject
MITOGEN ACTIVATED PROTEIN KINASES (ENZYMES)
en_US
dc.subject
REGULATION OF SIGNAL TRANSDUCTION (BIOCOMMUNICATION)
en_US
dc.subject
CANCER CELLS (CYTOPATHOLOGY)
en_US
dc.subject
CARCINOSTATICS + ANTINEOPLASTICS + ONCOSTATICS + CANCER REMEDIES (PHARMACY)
en_US
dc.subject
DRUG RESISTANCE (PHARMACOLOGY)
en_US
dc.title
Inhibition of oncogenic MAPK signaling in melanoma triggers a SOX2-dependent stemness program to promote adaptive drug resistance
en_US
dc.type
Doctoral Thesis
dc.rights.license
In Copyright - Non-Commercial Use Permitted
dc.date.published
2016
ethz.size
125 p.
en_US
ethz.code.ddc
DDC - DDC::6 - Technology, medicine and applied sciences::610 - Medical sciences, medicine
en_US
ethz.code.ddc
DDC - DDC::5 - Science::570 - Life sciences
en_US
ethz.identifier.diss
22929
en_US
ethz.identifier.nebis
010596039
ethz.publication.place
Zurich
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02539 - Institut für Molecular Health Sciences / Institute of Molecular Health Sciences::03630 - Krek, Wilhelm (ehemalig) / Krek, Wilhelm (former)
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02539 - Institut für Molecular Health Sciences / Institute of Molecular Health Sciences::03630 - Krek, Wilhelm (ehemalig) / Krek, Wilhelm (former)
ethz.date.deposited
2017-06-14T04:11:51Z
ethz.source
ECOL
ethz.identifier.importid
imp59366b884ab6b32725
ethz.ecolpid
eth:48677
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.date.embargoend
2019-02-24
ethz.rosetta.installDate
2017-07-25T11:44:32Z
ethz.rosetta.lastUpdated
2022-03-28T22:21:33Z
ethz.rosetta.versionExported
true
ethz.COinS
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Doctoral Thesis [28820]