I. Synthesis and Evaluation of Partially Fluorinated N-Alkyl Piperidines - II. Bicyclo3.2.0heptane as Core Structure for Conformational Locking of 1,3-bis-Pharmacophores, Exemplified by GABA

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Author
Vorberg, Raffael
Date
2016
Type
  • Doctoral Thesis
Rights / license
In Copyright - Non-Commercial Use Permitted
Permanent link
https://doi.org/10.3929/ethz-a-010859357
Publication status
published
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Contributors
Examiner: Carreira, Erick M.
Examiner: Diederich, François
Examiner: Müller, Klaus
Publisher
ETH Zurich
Subject
ORGANISCHE SYNTHESE (CHEMIE); FLUORORGANISCHE VERBINDUNGEN; APOLARE, HYDROPHOBE UND LIPOPHILE MOLEKÜLE UND INTERAKTIONEN (BIOPHYSIKALISCHE CHEMIE); ARZNEIMITTELENTWICKLUNG + ARZNEIMITTELDESIGN + ARZNEIMITTELENTDECKUNG; GAMMA-AMINOBUTTERSÄURE (NEUROLOGIE); CYCLISCHE KOHLENWASSERSTOFFE (ORGANISCHE CHEMIE); ORGANIC SYNTHESIS (CHEMISTRY); FLUORINE-ORGANIC COMPOUNDS; NON POLAR, HYDROPHOBIC AND LIPOPHILIC MOLECULES AND INTERACTIONS (BIOPHYSICAL CHEMISTRY); DRUG DEVELOPMENT + DRUG DESIGN + DRUG DISCOVERY (PHARMACY); GAMMA-AMINOBUTYRIC ACID (NEUROLOGY); CYCLIC HYDROCARBONS (ORGANIC CHEMISTRY)
Organisational unit
02020 - Departement Chemie und Angewandte Biowissenschaften / Department of Chemistry and Applied Biosciences
03511 - Carreira, Erick M.
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