Theses
Untergeordnete Publikationstypen
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Bachelor Thesis [46]
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Doctoral Thesis [25283]
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Habilitation Thesis [147]
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Master Thesis [1279]
Neueste Zugänge
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Bacterial and viral adaptation in ecologically complex systems
(2018)If we want to understand microbial diversity and find new ways to control infectious disease, it is important that we consider the variety of ecological factors that microorganisms normally encounter and how this influences their evolution. Our understanding of interactions between abiotic (e.g. antibiotics) and biotic (e.g. parasites) conditions, and how they affect microbial adaptation remains limited. Specifically, the role of viruses ...Doctoral Thesis -
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Signal Transduction in the General Stress Response in Sphingomonas Melonis Fr1
(2018)Doctoral Thesis -
Generative Temporal Models for Cosmology
(2018)In order to better understand the history of the universe and dark matter distributions, cosmologists run n-body simulations. Such simulations involve large amounts of points which can all effect each other. The computations are very expensive and evaluated at discrete points in time. In this project we come up with a novel model architecture within the generative adversarial network framework. The model is able to generate data for any ...Master Thesis -
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Decision Making under Uncertainty in Sustainable Energy Operations and Investments
(2018)The energy sector is undergoing a rapid transformation that gives rise to a variety of new optimization problems to solve. The goal of this thesis is to develop advanced analytical solutions for sustainable energy operations and investment problems that are subject to uncertainty. We consider case studies related to both industrial applications and consumer models, and cover problems related to energy efficiency, renewable energy, and ...Doctoral Thesis -
Dark-Field Imaging for Hard X-Ray Grating Interferometry: Predictive Models and Applications
(2018)Doctoral Thesis -
Statistical Methods for Better Hydrologic Predictions—Improving Parameter and Uncertainty Estimation
(2018)Doctoral Thesis -
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Building Block Approaches to the Synthesis of Lasso Peptides and Polycyclic Saturated N-Heterocycles
(2018)The first part of this dissertation describes the synthesis of peptide-based [1]rotaxanes (lasso peptides). Lasso peptides are bacterially produced natural products with unique interlocked structure that endows them exceptional proteolytic stability. Therefore, lasso peptides have been employed as scaffolds to enhance the proteolytic stability of linear peptides. This approach – so-called molecular grafting– has been achieved by biosynthetic ...Doctoral Thesis -
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The Molecular Basis for Biased Signalling by Human Cannabinoid CB2 Receptor
(2018)As part of our endocannabinoid system, human cannabinoid CB2 receptor is involved in regulation of many physiological processes. Due to its involvement in inflammation, CB2 is an interesting pharmacological target for treating conditions such as chronic pain, osteoporosis and Alzheimer’s disease. Although naturally existing cannabinoids have been used for millennia, and there are drugs targeting the endocannabinoid system, the mechanism ...Doctoral Thesis -
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Coherent Optical Phononics
(2018)In my thesis, I have strengthened the understanding of the vibrational dynamics of materials in response to stimulation by intense laser pulses. Vibrations of the crystal structure can be used to manipulate a material's properties in the electronic ground state on timescales less than a picosecond by changing the average ionic lattice that the electrons experience. In order to leverage this technique, the quantized vibrations of the ...Doctoral Thesis -
An Extended Coverage System on Chip for the Cellular Internet of Things
(2018)Billions of devices are expected to be connected to the so called Internet of Things (IoT) by 2020. Applications range from smart meters over cargo tracking to more exotic applications such as beehive temperature monitoring in remote areas. Many IoT applications require years of battery life and, needless to say in a billion devices network, low-cost chip-sets. Furthermore, numerous current and anticipated IoT applications are latency ...Doctoral Thesis -