Cooperative Light-Activated Iodine and Photoredox Catalysis for the Amination of Csp3-H Bonds
- Journal Article
An unprecedented method that makes use of the cooperative interplay between molecular iodine and photoredox catalysis has been developed for dual light-activated intramolecular benzylic C−H amination. Iodine serves as the catalyst for the formation of a new C−N bond by activating a remote Csp3−H bond (1,5-HAT process) under visible-light irradiation while the organic photoredox catalyst TPT effects the reoxidation of the molecular iodine catalyst. To explain the compatibility of the two involved photochemical steps, the key N−I bond activation was elucidated by computational methods. The new cooperative catalysis has important implications for the combination of non-metallic main-group catalysis with photocatalysis. Show more
Journal / seriesAngewandte Chemie. International Edition
Pages / Article No.
Organisational unit03736 - Reiher, Markus / Reiher, Markus
169120 - Development of quantum chemical methods for the calculation of structures, energetics and spectroscopy of transition metal complexes (SNF)
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