A functionalized polydimethyl siloxane chip for solvent-free, temperature actuated solid phase extraction
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This paper introduces a new approach for solvent-free solid phase extraction on a microfluidic chip. As a proof of concept study, we developed PDMS devices with pillar arrays to support the sorbent. Traditional reverse phase sorbent material was replaced by a thermo-responsive polymer, poly(Nisopropylacrylamide), that enables the extraction and release of biomolecules in aqueous media by varying the temperature. Two functionalization methods of the PDMS surface were investigated. This study is the starting point for future work in the field of environmental analysis involving immunodetection methods. Show more
Book title19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)
Pages / Article No.
PublisherChemical and Biological Microsystems Society
SubjectMicrofluidics; PDMS; PNIPAAm; Solid phase extraction; Thermo-responsive polymer
Organisational unit03807 - Dittrich, Petra / Dittrich, Petra
NotesPoster abstract. Poster presentation on October 28, 2015.
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