A functionalized polydimethyl siloxane chip for solvent-free, temperature actuated solid phase extraction
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Date
2015Type
- Other Conference Item
ETH Bibliography
yes
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Abstract
This paper introduces a new approach for solvent-free solid phase extraction on a microfluidic chip. As a proof of concept study, we developed PDMS devices with pillar arrays to support the sorbent. Traditional reverse phase sorbent material was replaced by a thermo-responsive polymer, poly(Nisopropylacrylamide), that enables the extraction and release of biomolecules in aqueous media by varying the temperature. Two functionalization methods of the PDMS surface were investigated. This study is the starting point for future work in the field of environmental analysis involving
immunodetection methods. Show more
Publication status
publishedBook title
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)Pages / Article No.
Publisher
Chemical and Biological Microsystems SocietyEvent
Subject
Microfluidics; PDMS; PNIPAAm; Solid phase extraction; Thermo-responsive polymerOrganisational unit
03807 - Dittrich, Petra / Dittrich, Petra
Notes
Poster abstract. Poster presentation on October 28, 2015.More
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ETH Bibliography
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