Show simple item record

dc.contributor.author
Elsaesser, Lore
dc.contributor.author
Breuninger, Holger
dc.contributor.author
Sánchez-Rodríguez, Clara
dc.contributor.author
Ivakov, Alexander
dc.contributor.author
Laux, Thomas
dc.contributor.author
Findlay, Kim
dc.contributor.author
Persson, Staffan
dc.contributor.author
Lenhard, Michael
dc.contributor.author
Fujikura, Ushio
dc.date.accessioned
2018-10-31T16:29:56Z
dc.date.available
2017-09-14T06:12:43Z
dc.date.available
2017-09-14T11:57:18Z
dc.date.available
2018-10-31T16:29:56Z
dc.date.issued
2014-09-18
dc.identifier.issn
1553-7390
dc.identifier.issn
1553-7404
dc.identifier.other
10.1371/journal.pgen.1004627
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/184743
dc.identifier.doi
10.3929/ethz-b-000184743
dc.description.abstract
Growth of plant organs relies on cell proliferation and expansion. While an increasingly detailed picture about the control of cell proliferation is emerging, our knowledge about the control of cell expansion remains more limited. We demonstrate here that the internal-motor kinesin AtKINESIN-13A (AtKIN13A) limits cell expansion and cell size in Arabidopsis thaliana, with loss-of-function atkin13a mutants forming larger petals with larger cells. The homolog, AtKINESIN-13B, also affects cell expansion and double mutants display growth, gametophytic and early embryonic defects, indicating a redundant role of the two genes. AtKIN13A is known to depolymerize microtubules and influence Golgi motility and distribution. Consistent with this function, AtKIN13A interacts genetically with ANGUSTIFOLIA, encoding a regulator of Golgi dynamics. Reduced AtKIN13A activity alters cell wall structure as assessed by Fourier-transformed infrared-spectroscopy and triggers signalling via the THESEUS1-dependent cell-wall integrity pathway, which in turn promotes the excess cell expansion in the atkin13a mutant. Thus, our results indicate that the intracellular activity of AtKIN13A regulates cell expansion and wall architecture via THESEUS1, providing a compelling case of interplay between cell wall integrity sensing and expansion.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Public Library of Science (PLoS)
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Atkinesin-13A Modulates Cell-Wall Synthesis and Cell Expansion in Arabidopsis thaliana via the THESEUS1 Pathway
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
PLoS Genetics
ethz.journal.volume
10
en_US
ethz.journal.issue
9
en_US
ethz.journal.abbreviated
PLoS Genet
ethz.pages.start
e1004627
en_US
ethz.size
15 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.publication.place
San Francisco, CA
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02541 - Institut für Molekulare Pflanzenbiologie / Institute of Molecular Plant Biology::09530 - Sánchez Rodríguez, Clara / Sánchez Rodríguez, Clara
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02030 - Dep. Biologie / Dep. of Biology::02541 - Institut für Molekulare Pflanzenbiologie / Institute of Molecular Plant Biology::09530 - Sánchez Rodríguez, Clara / Sánchez Rodríguez, Clara
en_US
ethz.date.deposited
2017-09-14T06:12:44Z
ethz.source
FORM
ethz.eth
no
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-09-14T11:57:22Z
ethz.rosetta.lastUpdated
2018-10-31T16:30:03Z
ethz.rosetta.versionExported
true
ethz.COinS
ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.atitle=Atkinesin-13A%20Modulates%20Cell-Wall%20Synthesis%20and%20Cell%20Expansion%20in%20Arabidopsis%20thaliana%20via%20the%20THESEUS1%20Pathway&rft.jtitle=PLoS%20Genetics&rft.date=2014-09-18&rft.volume=10&rft.issue=9&rft.spage=e1004627&rft.issn=1553-7390&1553-7404&rft.au=Elsaesser,%20Lore&Breuninger,%20Holger&S%C3%A1nchez-Rodr%C3%ADguez,%20Clara&Ivakov,%20Alexander&Laux,%20Thomas&rft.genre=article&rft_id=info:doi/10.1371/journal.pgen.1004627&
 Search print copy at ETH Library

Files in this item

Thumbnail

Publication type

Show simple item record