Dittrich, Petra S.
Urban, Gerald A.
- Review Article
Multiplexed point-of-care testing (xPOCT), which is simultaneous on-site detection of different analytes from a single specimen, has recently gained increasing importance for clinical diagnostics, with emerging applications in resource-limited settings (such as in the developing world, in doctors’ offices, or directly at home). Nevertheless, only single-analyte approaches are typically considered as the major paradigm in many reviews of point-of-care testing. Here, we comprehensively review the present diagnostic systems and techniques for xPOCT applications. Different multiplexing technologies (e.g., bead- or array-based systems) are considered along with their detection methods (e.g., electrochemical or optical). We also address the unmet needs and challenges of xPOCT. Finally, we critically summarize the in-field applicability and the future perspectives of the presented approaches Show more
Journal / seriesTrends in biotechnology
Pages / Article No.
Subjectlab-on-a-chip (LOC); microfluidics; multianalyte analysis; multiplexing; on-site testing; point-of-care testing (POCT)
Organisational unit03807 - Dittrich, Petra / Dittrich, Petra
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