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dc.contributor.author
Hauser, Tobias U.
dc.contributor.author
Moutoussis, Michael
dc.contributor.author
Iannaccone, Reto
dc.contributor.author
Brem, Silvia
dc.contributor.author
Walitza, Susanne
dc.contributor.author
Drechsler, Renate
dc.contributor.author
Dayan, Peter
dc.contributor.author
Dolan, Raymond J.
dc.date.accessioned
2017-10-12T07:53:30Z
dc.date.available
2017-10-06T03:11:41Z
dc.date.available
2017-10-12T07:52:44Z
dc.date.available
2017-10-12T07:53:30Z
dc.date.issued
2017-04
dc.identifier.issn
1553-734X
dc.identifier.issn
1553-7358
dc.identifier.other
10.1371/journal.pcbi.1005440
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/191384
dc.identifier.doi
10.3929/ethz-b-000191384
dc.description.abstract
Patients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making. However, excess caution in decision making may also lead to better performance in specific situations where the cost of extended deliberation is small. We compared 16 juvenile OCD patients with 16 matched healthy controls whilst they performed a sequential information gathering task under different external cost conditions. We found that patients with OCD outperformed healthy controls, winning significantly more points. The groups also differed in the number of draws required prior to committing to a decision, but not in decision accuracy. A novel Bayesian computational model revealed that subjective sampling costs arose as a non-linear function of sampling, closely resembling an escalating urgency signal. Group difference in performance was best explained by a later emergence of these subjective costs in the OCD group, also evident in an increased decision threshold. Our findings present a novel computational model and suggest that enhanced information gathering in OCD can be accounted for by a higher decision threshold arising out of an altered perception of costs that, in some specific contexts, may be advantageous.
en_US
dc.language.iso
en
en_US
dc.publisher
Public Library of Science
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD)
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2017-04-12
ethz.journal.title
PLoS Computational Biology
ethz.journal.volume
13
en_US
ethz.journal.issue
4
en_US
ethz.journal.abbreviated
PLOS comput. biol.
ethz.pages.start
1
en_US
ethz.pages.end
19
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
San Francicsco, CA
en_US
ethz.publication.status
published
en_US
ethz.date.deposited
2017-10-06T03:12:03Z
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-10-12T07:52:47Z
ethz.rosetta.lastUpdated
2018-11-05T21:30:40Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
ethz.COinS
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