An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket
Debler, Erik W.
Wilson, Ian A.
- Journal Article
Journal / seriesProceedings of the National Academy of Sciences of the United States of America
PublisherNational Academy of Sciences
Subjectcatalytic antibody; crystal structure; enzyme design; enzyme mechanism; proton transfer
Organisational unit03492 - Hilvert, Donald
NotesApproved September 11 2009, Received for review March 11 2009.
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