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dc.contributor.author
Stapley, Jessica
dc.contributor.author
Feulner, Philine G.D.
dc.contributor.author
Johnston, Susan E.
dc.contributor.author
Santure, Anna W.
dc.contributor.author
Smadja, Carole M.
dc.date.accessioned
2017-11-10T10:09:44Z
dc.date.available
2017-11-09T15:01:16Z
dc.date.available
2017-11-10T10:09:44Z
dc.date.issued
2017-12-19
dc.identifier.issn
0962-8436
dc.identifier.issn
1471-2970
dc.identifier.other
10.1098/rstb.2016.0455
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/206765
dc.identifier.doi
10.3929/ethz-b-000206765
dc.description.abstract
Recombination, the exchange of DNA between maternal and paternal chromosomes during meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms. While the role of recombination in the evolution of sex has received theoretical and empirical attention, less is known about how recombination rate itself evolves and what influence this has on evolutionary processes within sexually reproducing organisms. Here, we explore the patterns of, and processes governing recombination in eukaryotes. We summarize patterns of variation, integrating current knowledge with an analysis of linkage map data in 353 organisms. We then discuss proximate and ultimate processes governing recombination rate variation and consider how these influence evolutionary processes. Genome-wide recombination rates (cM/Mb) can vary more than tenfold across eukaryotes, and there is large variation in the distribution of recombination events across closely related taxa, populations and individuals. We discuss how variation in rate and distribution relates to genome architecture, genetic and epigenetic mechanisms, sex, environmental perturbations and variable selective pressures. There has been great progress in determining the molecular mechanisms governing recombination, and with the continued development of new modelling and empirical approaches, there is now also great opportunity to further our understanding of how and why recombination rate varies.
en_US
dc.format
application/pdf
dc.language.iso
en
en_US
dc.publisher
The Royal Society
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Crossing over
en_US
dc.subject
Meiosis
en_US
dc.subject
Genetic linkage
en_US
dc.subject
Evolution
en_US
dc.subject
Adaptation
en_US
dc.subject
Genomic architecture
en_US
dc.title
Variation in recombination frequency and distribution across eukaryotes: patterns and processes
en_US
dc.type
Review Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2017-11-06
ethz.journal.title
Philosophical Transactions of the Royal Society B: Biological Sciences
ethz.journal.volume
372
en_US
ethz.journal.issue
1736
en_US
ethz.journal.abbreviated
Philos. trans. - R. Soc., Biol. Sci.
ethz.pages.start
20160455
en_US
ethz.size
18 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.code.ddc
DDC - DDC::5 - Science::570 - Life sciences
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03706 - Widmer, Alexander / Widmer, Alexander
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03706 - Widmer, Alexander / Widmer, Alexander
en_US
ethz.date.deposited
2017-11-09T15:01:17Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-11-10T10:09:56Z
ethz.rosetta.lastUpdated
2021-02-14T20:08:40Z
ethz.rosetta.versionExported
true
ethz.COinS
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