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dc.contributor.author
Kombrink, Anja
dc.contributor.author
Rovenich, Hanna
dc.contributor.author
Shi-Kunne, Xiaoqian
dc.contributor.author
Rojas-Padilla, Eduardo
dc.contributor.author
van den Berg, Grardy C. M.
dc.contributor.author
Domazakis, Emmanouil
dc.contributor.author
de Jonge, Ronnie
dc.contributor.author
Valkenburg, Dirk-Jan
dc.contributor.author
Sanchez-Vallet, Andrea
dc.contributor.author
Seidl, Michael F.
dc.contributor.author
Thomma, Bart P.H.J.
dc.date.accessioned
2018-01-10T09:08:41Z
dc.date.available
2017-12-05T09:46:22Z
dc.date.available
2018-01-10T09:08:41Z
dc.date.issued
2017-04-04
dc.identifier.issn
1464-6722
dc.identifier.issn
1364-3703
dc.identifier.other
10.1111/mpp.12520
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/217279
dc.identifier.doi
10.3929/ethz-b-000217279
dc.description.abstract
Chitin-binding lysin motif (LysM) effectors contribute to the virulence of various plant-pathogenic fungi that are causal agents of foliar diseases. Here, we report the LysM effectors of the soil-borne fungal vascular wilt pathogen Verticillium dahliae. Comparative genomics revealed three core LysM effectors that are conserved in a collection of V. dahliae strains. Remarkably, and in contrast with the previously studied LysM effectors of other plant pathogens, no expression of core LysM effectors was monitored in planta in a taxonomically diverse panel of host plants. Moreover, targeted deletion of the individual LysM effector genes in V. dahliae strain JR2 did not compromise virulence in infections on Arabidopsis, tomato or Nicotiana benthamiana. Interestingly, an additional lineage-specific LysM effector is encoded in the genome of V. dahliae strain VdLs17, but not in any other V. dahliae strain sequenced to date. Remarkably, this lineage-specific effector is expressed in planta and contributes to the virulence of V. dahliae strain VdLs17 on tomato, but not on Arabidopsis or N. benthamiana. Functional analysis revealed that this LysM effector binds chitin, is able to suppress chitin-induced immune responses and protects fungal hyphae against hydrolysis by plant hydrolytic enzymes. Thus, in contrast with the core LysM effectors of V. dahliae, this lineage-specific LysM effector of strain VdLs17 contributes to virulence in planta.
en_US
dc.language.iso
en
en_US
dc.publisher
Wiley-Blackwell
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
aggressiveness
en_US
dc.subject
chitin
en_US
dc.subject
comparative genomics
en_US
dc.subject
hyphal protection
en_US
dc.subject
lineage-specific effecto
en_US
dc.subject
tomato
en_US
dc.subject
vascular wilt disease
en_US
dc.title
Verticillium dahliae LysM effectors differentially contribute to virulence on plant hosts
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
ethz.journal.title
Molecular Plant Pathology
ethz.journal.volume
18
en_US
ethz.journal.issue
4
en_US
ethz.journal.abbreviated
Mol. plant pathol.
ethz.pages.start
596
en_US
ethz.pages.end
608
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.publication.place
Oxford
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology::03516 - McDonald, Bruce / McDonald, Bruce
ethz.date.deposited
2017-12-05T09:46:23Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-01-10T09:08:45Z
ethz.rosetta.lastUpdated
2018-12-02T08:43:33Z
ethz.rosetta.versionExported
true
ethz.COinS
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