Modulation and modeling of monoclonal antibody N-linked glycosylation in mammalian cell perfusion reactors

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Author
Karst, Daniel J.
Scibona, Ernesto
Serra, Elisa
Bielser, Jean-Marc
Souquet, Jonathan
Stettler, Matthieu
Broly, Herve
Soos, Miroslav
Morbidelli, Massimo
Villiger, Thomas K.
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Date
2017-09
Type
  • Journal Article
Publication status
published
External links
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Journal / series
Biotechnology and Bioengineering
Volume
114(9)
Pages / Article No.
1978 - 1990
Publisher
Wiley
Subject
N-linked glycosylation; mammalian cell culture; perfusion bioreactor; mathematical model; monoclonal antibody
Organisational unit
03451 - Morbidelli, Massimo / Morbidelli, Massimo  
02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.
Funding
150744 - Development and Optimization of Continuous Production of Therapeutic Proteins (SNF)
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Citations
Cited 10 times in Web of Science
ETH Bibliography
yes
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