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dc.contributor.author
Röhrnbauer, Barbara
dc.contributor.author
Betschart, Cornelia
dc.contributor.author
Perucchini, Daniele
dc.contributor.author
Bajka, Michael
dc.contributor.author
Fink, Daniel
dc.contributor.author
Maake, Caroline
dc.contributor.author
Mazza, Edoardo
dc.contributor.author
Scheiner, David A.
dc.date.accessioned
2018-01-03T10:05:35Z
dc.date.available
2018-01-03T10:05:35Z
dc.date.available
2017-12-06T05:49:35Z
dc.date.available
2017-12-18T15:45:52Z
dc.date.issued
2017
dc.identifier.issn
2045-2322
dc.identifier.other
10.1038/s41598-017-16083-0
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/239046
dc.identifier.doi
10.3929/ethz-b-000217950
dc.description.abstract
Little is known about the mechanical properties of pelvic floor structures and their role in the course and treatment of pelvic organ prolapse (POP). We hypothesize that in vivo mechanical properties of the vaginal wall are related to the appearance of POP and pre-and post-operative states. We used a suction device for intravaginal application, the aspiration device, to evaluate two in vivo mechanical parameters of the anterior vaginal wall, the load dependent tissue displacement and the initial displacement, by image analysis in pre- and post-menopausal women with (POP) and without (control) cystocele (POP: pre-menopausal: N = 6, post-menopausal: N = 19, control: pre-menopausal: N = 17, post-menopausal: N = 6). Mechanical parameters in women with and without cystocele and pre- and post-operative parameters were compared. Statistically significant differences were observed between the two mechanical parameters in pre- and post-operative states (P = 0.04, P = 0.03), but not between the parameters for women with and without cystocele (P = 0.92, P = 0.75). The mechanical behavior of pelvic floor structures is influenced by factors such as POP, age or estrogenization that are apparent at different length scales, which cannot be separated by the aspiration based biomechanical measurements. When comparing pre- and post-operative states of the same patient, a firmer tissue response was observed after intervention.
en_US
dc.format
application/pdf
dc.language.iso
en
en_US
dc.publisher
Nature Publishing Group
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.title
Measuring tissue displacement of the anterior vaginal wall using the novel aspiration technique in vivo
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2017-11-23
ethz.journal.title
Scientific Reports
ethz.journal.volume
7
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
Sci Rep
ethz.pages.start
16141
en_US
ethz.size
7 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
London
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02618 - Institut für Mechanische Systeme / Institute of Mechanical Systems::03605 - Mazza, Edoardo / Mazza, Edoardo
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02130 - Dep. Maschinenbau und Verfahrenstechnik / Dep. of Mechanical and Process Eng.::02618 - Institut für Mechanische Systeme / Institute of Mechanical Systems::03605 - Mazza, Edoardo / Mazza, Edoardo
en_US
ethz.date.deposited
2017-12-06T05:49:36Z
ethz.source
FORM
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-02-07T07:50:13Z
ethz.rosetta.lastUpdated
2020-02-15T11:07:03Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/225105
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/217950
ethz.COinS
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