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dc.contributor.author
Koudou, Benjamin G.
dc.contributor.author
Ghattas, Hala
dc.contributor.author
Essé, Clémence
dc.contributor.author
Nsanzabana, Christian
dc.contributor.author
Rohner, Fabian
dc.contributor.author
Utzinger, Jürg
dc.contributor.author
Faragher, Brian E.
dc.contributor.author
Tschannen, Andres B.
dc.date.accessioned
2019-06-06T14:50:55Z
dc.date.available
2017-06-09T06:18:26Z
dc.date.available
2019-06-06T14:50:55Z
dc.date.issued
2010-09-22
dc.identifier.issn
1756-3305
dc.identifier.other
10.1186/1756-3305-3-91
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/24443
dc.identifier.doi
10.3929/ethz-b-000024443
dc.description.abstract
Background Long-lasting insecticidal nets (LLINs) are an important tool for controlling malaria. Much attention has been devoted to determine both the effect of LLINs on the reduction of Plasmodium infection rate and on clinically-confirmed malaria cases in sub-Saharan Africa. We carried out an epidemiological study to investigate whether LLINs impact on Plasmodium prevalence rate and the proportion of clinically-confirmed malaria cases, in five villages in the district of Toumodi, central Côte d'Ivoire. Methods From April 2007 to November 2008, a community-based malaria control programme was implemented in the study villages, which involved large-scale distribution of LLINs, and training and sensitization activities within the community. We determined the effect of this programme on Plasmodium prevalence rate, clinically-confirmed malaria cases and proportion of high parasitaemia rates in children aged 6-59 months through a series of cross-sectional surveys starting in April 2007 and repeated once every 6 months. Results We observed a significant decrease in the mean P. falciparum prevalence rate from April 2007 to April 2008 (p = 0.029). An opposite trend was observed from November 2007 to November 2008 when P. falciparum prevalence rate increased significantly (p = 0.003). Highly significant decreases in the proportions of clinical malaria cases were observed between April 2007 and April 2008 (p < 0.001), and between November 2007 and November 2008 (p = 0.001). Conclusions Large-scale distribution of LLINs, accompanied by training and sensitization activities, significantly reduced Plasmodium prevalence rates among young children in the first year of the project, whereas overall clinical malaria rates dropped over the entire 18-month project period. A decrease in community motivation to sleep under bed nets, perhaps along with changing patterns of malaria transmission, might explain the observed increase in the Plasmodium prevalence rate between November 2007 and November 2008.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/2.0/
dc.title
The use of insecticide-treated nets for reducing malaria morbidity among children aged 6-59 months, in an area of high malaria transmission in central Côte d'Ivoire
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 2.0 Generic
ethz.journal.title
Parasites & Vectors
ethz.journal.volume
3
en_US
ethz.journal.issue
1
en_US
ethz.journal.abbreviated
Parasit. vectors
ethz.pages.start
91
en_US
ethz.size
11 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.date.deposited
2017-06-09T06:18:47Z
ethz.source
ECIT
ethz.identifier.importid
imp59364d26816c724158
ethz.ecitpid
pub:39852
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2017-07-25T18:52:52Z
ethz.rosetta.lastUpdated
2024-02-02T08:14:10Z
ethz.rosetta.versionExported
true
ethz.COinS
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