Show simple item record

dc.contributor.author
Wegner, K. Mathias
dc.contributor.author
Kalbe, Martin
dc.contributor.author
Milinski, Manfred
dc.contributor.author
Reusch, Thorsten B.H.
dc.date.accessioned
2018-05-24T07:44:22Z
dc.date.available
2018-05-24T07:36:18Z
dc.date.available
2018-05-24T07:44:22Z
dc.date.issued
2008-04
dc.identifier.issn
1471-2148
dc.identifier.other
10.1186/1471-2148-8-124
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/265816
dc.identifier.doi
10.3929/ethz-a-005751854
dc.description.abstract
Background Ecological interaction strength may increase under environmental stress including temperature. How such stress enhances and interacts with parasite selection is almost unknown. We studied the importance of resistance genes of the major histocompatibility complex (MHC) class II in 14 families of three-spined sticklebacks Gasterosteus aculeatus exposed to their natural macroparasites in field enclosures in the extreme summer of 2003. Results After a mass die-off during the 2003-European heat wave killing 78% of 277 experimental fish, we found strong differences in survival among and within families. In families with higher average parasite load fewer individuals survived. Multivariate analysis revealed that the composition of the infecting parasite fauna was family specific. Within families, individuals with an intermediate number of MHC class IIB sequence variants survived best and had the lowest parasite load among survivors, suggesting a direct functional link between MHC diversity and fitness. The within family MHC effects were, however, small compared to between family effects, suggesting that other genetic components or non-genetic effects were also important. Conclusion The correlation between parasite load and mortality that we found at both individual and family level might have appeared only in the extraordinary heatwave of 2003. Due to global warming the frequency of extreme climatic events is predicted to increase, which might intensify costs of parasitism and enhance selection on immune genes.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
BioMed Central
en_US
dc.rights.uri
http://creativecommons.org/licenses/by/2.0/
dc.subject
Major histocompatibility complex
en_US
dc.subject
Major histocompatibility complex class
en_US
dc.subject
Parasite species
en_US
dc.subject
Parasite load
en_US
dc.subject
Infection itensity
en_US
dc.title
Mortality selection during the 2003 European heat wave in three-spined sticklebacks: effects of parasites and MHC genotype
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 2.0 Generic
dc.date.published
2008-04-30
ethz.journal.title
BMC Evolutionary Biology
ethz.journal.volume
8
en_US
ethz.journal.abbreviated
BMC evol. biol.
ethz.pages.start
124
en_US
ethz.size
12 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.code.ddc
5 - Science::590 - Zoological sciences
en_US
ethz.identifier.wos
ethz.publication.place
London
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02350 - Dep. Umweltsystemwissenschaften / Dep. of Environmental Systems Science::02720 - Institut für Integrative Biologie / Institute of Integrative Biology
en_US
ethz.leitzahl
03330 - Schmid-Hempel, Paul
en_US
ethz.leitzahl.certified
03330 - Schmid-Hempel, Paul
ethz.date.deposited
2017-06-08T19:01:10Z
ethz.source
ECOL
ethz.source
ECIT
ethz.identifier.importid
imp59366acd9e62d72773
ethz.identifier.importid
imp59364be062f7e85771
ethz.ecolpid
eth:41380
ethz.ecitpid
pub:20632
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2018-05-24T07:36:43Z
ethz.rosetta.lastUpdated
2019-02-03T01:38:50Z
ethz.rosetta.exportRequired
true
ethz.rosetta.versionExported
true
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/150963
dc.identifier.olduri
http://hdl.handle.net/20.500.11850/9687
ethz.COinS
ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.atitle=Mortality%20selection%20during%20the%202003%20European%20heat%20wave%20in%20three-spined%20sticklebacks:%20effects%20of%20parasites%20and%20MHC%20genotype&rft.jtitle=BMC%20Evolutionary%20Biology&rft.date=2008-04&rft.volume=8&rft.spage=124&rft.issn=1471-2148&rft.au=Wegner,%20K.%20Mathias&Kalbe,%20Martin&Milinski,%20Manfred&Reusch,%20Thorsten%20B.H.&rft.genre=article&
 Search via SFX

Files in this item

Thumbnail

Publication type

Show simple item record