Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics
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Date
2018-07-13Type
- Journal Article
Publication status
publishedJournal / series
ACS Infectious DiseasesVolume
Pages / Article No.
Publisher
American Chemical SocietySubject
aminoglycosides; structure-activity relationship; minoglycoside-modifying enzymes; ribosomal methyltransferases; cell-free translation assaysMore
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